SFPQBusiness Directories,Company Directories

Company Name: Corporate Name:	SFPQ
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Company Address:	425 Boul DE Maisonneuve O #100,MONTREAL,QC,Canada
ZIP Code: Postal Code:	H3A3G5
Telephone Number:	5148444487
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USA SIC Code(Standard Industrial Classification Code):	863101
USA SIC Description:	Labor Organizations
Number of Employees:	1 to 4
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Credit History: Credit Report:	Institution
Contact Person:	Michel Sawyer
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A conserved role for the ALS-linked splicing factor SFPQ in . . . - Nature
SFPQ is a splicing factor and its mutations are associated to amyotrophic lateral sclerosis (ALS) patients Here, the authors show that SFPQ represses the use of pathogenic cryptic last exons
SFPQ and NONO suppress RNA:DNA-hybrid-related telomere instability
Our data identify the RNA binding proteins SFPQ and NONO as novel regulators at telomeres that collaborate to ensure telomere integrity by suppressing telomere fragility and homologous
SFPQ - Wikipedia
SFPQ Splicing factor, proline- and glutamine-rich is a protein that in humans is encoded by the SFPQ gene [5][6]
Smad4 sequestered in SFPQ condensates prevents TGF-β . . . - Cell Press
In this study, we discovered that SFPQ could sequester tumor suppressor Smad4 in its condensates to suppress Smad transcriptional activation Specifically, SFPQ dissociated the Smad3-Smad4 complex and blocked the chromatin occupancy of Smad4
The RNA-binding protein SFPQ preserves long-intron splicing and . . . - eLife
Transcriptome and eCLIP analyses in mouse and human reveal splicing factor proline glutamine rich (SFPQ) as a conserved and critical guardian of long-intron integrity, splicing, and circular RNA (circRNA) production
SFPQ splicing factor proline and glutamine rich [ (human)]
AR-induced long non-coding RNA LINC01503 facilitates proliferation and metastasis via the SFPQ-FOSL1 axis in nasopharyngeal carcinoma Splicing factor proline- and glutamine-rich (SFPQ) protein regulates platinum response in ovarian cancer-modulating SRSF2 activity
生研院冯新华实验室在Developmental Cell在线发文揭示SFPQ 凝聚体阻断TGF-β抑制肿瘤发生的机制
该研究发现一种叫做SFPQ的RNA结合蛋白直接结合Smad4，通过相分离抑制了Smad4的转录活性，从而阻断了TGF-β信号的抑瘤功能。
富脯氨酸和谷氨酰胺的剪接因子（SFPQ）基因 | MCE
关于 SFPQ Cytogenetic location: 1p34 3 Genomic coordinates (GRCh38): 1:35,176,380-35,193,145 (from NCBI) This gene has 11 transcripts (splice variants), 216 orthologues, 7 paralogues and is associated with 60 phenotypes Ubiquitous expression in bone marrow (RPKM 84 2), skin (RPKM 34 9) and 25 other tissues
SFPQ基因的功能与作用机制解析 - 八方基因
本文将详细介绍SFPQ基因的功能、作用机制、涉及的信号通路以及与疾病的关系，帮助读者全面理解这一重要的剪接因子基因。