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Adrenoleukodystrophy (ALD) - Johns Hopkins Medicine What is ALD? Adrenoleukodystrophy (ALD) is a genetic condition that damages the membrane (myelin sheath) that covers nerve cells in the brain and spinal cord Myelin acts as insulation around the nerve fibers
Adrenoleukodystrophy (ALD): Causes, Types, Symptoms, Prognosis About 1 in 17,000 people are born with a genetic disease called adrenoleukodystrophy (ALD) This severe brain disorder mainly affects boys and men There’s no cure yet for it, but a diagnosis
Adrenoleukodystrophy - Wikipedia Adrenoleukodystrophy (ALD) is a disease linked to the X chromosome It is a result of fatty acid buildup caused by failure of peroxisomal fatty acid beta oxidation which results in the accumulation of very long chain fatty acids in tissues throughout the body
Adrenoleukodystrophy - Symptoms and causes - Mayo Clinic In adrenoleukodystrophy (ALD), your body can't break down very long-chain fatty acids (VLCFAs), causing saturated VLCFA s to build up in your brain, nervous system and adrenal gland The most common type of ALD is X-linked ALD, which is caused by a genetic defect on the X chromosome
Adrenoleukodystrophy (ALD) - Boston Childrens Hospital Adrenoleukodystrophy (ALD) is a rare genetic condition that affects males and females differently In childhood, boys are primarily affected Girls are not typically affected, though they may develop symptoms as adults