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  • Adrenoleukodystrophy - Symptoms and causes - Mayo Clinic
    In adrenoleukodystrophy (ALD), your body can't break down very long-chain fatty acids (VLCFAs), causing saturated VLCFA s to build up in your brain, nervous system and adrenal gland The most common type of ALD is X-linked ALD, which is caused by a genetic defect on the X chromosome
  • Adrenoleukodystrophy - Wikipedia
    Adrenoleukodystrophy (ALD) is a disease linked to the X chromosome It is a result of fatty acid buildup caused by failure of peroxisomal fatty acid beta oxidation which results in the accumulation of very long chain fatty acids in tissues throughout the body
  • Adrenoleukodystrophy (ALD) - Johns Hopkins Medicine
    What is ALD? Adrenoleukodystrophy (ALD) is a genetic condition that damages the membrane (myelin sheath) that covers nerve cells in the brain and spinal cord Myelin acts as insulation around the nerve fibers
  • Adrenoleukodystrophy (ALD): Causes, Types, Symptoms, Prognosis - WebMD
    About 1 in 17,000 people are born with a genetic disease called adrenoleukodystrophy (ALD) This severe brain disorder mainly affects boys and men There’s no cure yet for it, but a diagnosis
  • Adrenoleukodystrophy - StatPearls - NCBI Bookshelf
    Adrenoleukodystrophy is a rare genetic peroxisomal disorder characterized by the abnormal metabolism of very long-chain fatty acids (VLCFAs) due to mutations in the ABCD1 gene This leads to the accumulation of VLCFAs, particularly affecting the brain, spinal cord, adrenal glands, and testes
  • ALD: Adrenoleukodystrophy, Disease, X-Linked - Cleveland Clinic
    Adrenoleukodystrophy (ALD) is a genetic disorder It affects the nervous system and adrenal glands ALD symptoms include behavioral changes
  • Adrenoleukodystrophy | About the Disease | GARD
    It is caused by variations in the ABCD1 gene that lead to an inability to break down very long–chain fatty acids (VLCFAs) which can accumulate in the brain and adrenal glands This can result in progressive loss of the fatty covering (myelin) that surrounds the nerves in the brain and spinal cord
  • Adrenoleukodystrophy (ALD) | Boston Childrens Hospital
    What is adrenoleukodystrophy? Adrenoleukodystrophy (ALD) is a rare genetic condition that affects males and females differently In childhood, boys are primarily affected Girls are not typically affected, though they may develop symptoms as adults




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