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Connexin - Wikipedia Connexins are synthesized on ER-bound ribosomes and inserted into the ER cotranslationally This is followed by oligomerization between the ER and trans-Golgi network (depending on the connexin type) into connexons, which are then delivered to the membrane via the actin or microtubule networks
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Connexins: Mechanisms regulating protein levels and intercellular . . . Gap junction channels are comprised of integral multi-pass transmembrane proteins called connexins [1, 2] Connexins have four transmembrane domains that are linked by one intracellular loop, two extracellular loops, and have N- and C-terminal cytoplasmic domains
Connexin Definition - Anatomy and Physiology I Key Term | Fiveable Describe the structural features of connexin proteins and how they contribute to the formation of gap junction channels Connexin proteins have a characteristic structure, with four transmembrane domains, two extracellular loops, and intracellular amino- and carboxy-terminal domains
Connexin - an overview | ScienceDirect Topics Connexin (Cx) is defined as a family of transmembrane proteins that self-associate to form gap junctions, facilitating cell–cell connections essential for electrical transduction, signaling, and nutrition
Diversity in connexin biology - Journal of Biological Chemistry Over 35 years ago the cell biology community was introduced to connexins as the subunit employed to assemble semicrystalline clusters of intercellular channels that had been well described morphologically as gap junctions
About Us - Connexin Connexin, established in 2006, is a UK-based smarter technology provider with industry-leading services across four areas: Cities, Buildings, Utilities and Broadband Passionate about bridging digital divides for all, Connexin was one of the first challenger brands to enter the Hull broadband market and shake up the legacy local monopoly
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Connexins and Disease - PMC In the present work, we review current knowledge on the role of connexins in diseases associated with the heart, nervous system, cochlea, and skin, as well as cancer and pleiotropic syndromes such as oculodentodigital dysplasia (ODDD)