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Bempedoic acid: Uses, Dosage, Side Effects, Warnings - Drugs. com Bempedoic acid (brand name Nexletol) is an oral, non-statin, LDL cholesterol-lowering treatment that may be used in adults to: lower the risk of heart attack and heart procedures (for example stent placement or bypass surgery), in those unable to take recommended statin treatment (a cholesterol-lowering medicine), or are not taking a statin, who:
Bempedoic acid (oral route) - Side effects dosage - Mayo Clinic Description Bempedoic acid is used together with diet and other cholesterol-lowering medicines to reduce bad cholesterol (LDL) in patients with primary hyperlipidemia (high blood cholesterol), including heterozygous familial hypercholesterolemia (HeFH) Bempedoic acid is also used to lower the risk of heart attack and heart procedures (eg, stent placement or bypass surgery) in patients who are
Bempedoic acid: mechanism, evidence, safety, and guideline . . . Lowering low-density lipoprotein cholesterol remains foundational in reducing atherosclerotic cardiovascular disease Statins, ezetimibe, and PCSK9 inhibitors have established roles Bempedoic acid is an oral ATP‐citrate lyase (ACLY) inhibitor, relatively recently added to the lipid-lowering armamentarium In statin-intolerant or statin-suboptimal patients, plus in combination therapy, it
AACE Dyslipidemia Guidelines (2025 Updates) - Clinical Advisor The task force recommended against the use of bempedoic acid along with standard care among adults with dyslipidemia without ASCVD and with tolerance to other lipid-lowering medications
Bempedoic Acid: Lipid Lowering for Cardiovascular Disease . . . Bempedoic acid was associated with increases in uric acid levels and cholelithiasis, but numerically fewer events of myalgia and new-onset diabetes These findings confirm that bempedoic acid is an effective approach to reduce cardiovascular outcomes in high-risk patients with statin intolerance who require further reduction in LDL-C
Efficacy of Bempedoic Acid, Novel Treatment for Elevated LDL . . . By Anthony Rice Bempedoic acid is a novel non-statin drug produced by Esperion Therapeutics to treat hypercholesterolemia, elevated levels of low-density lipoprotein (LDL) cholesterol in the blood 1 In the double-blind, placebo-controlled, phase 3 2022 CLEAR Outcomes trial conducted by Esperion, bempedoic acid treatment was associated with reductions in major adverse cardiovascular events
Nexletol (bempedoic acid): Uses, Side Effects . . . - GoodRx Nexletol (bempedoic acid) is a brand-name medication that treats adults with high cholesterol, including those with a genetic condition called familial hypercholesterolemia It also helps lower the risk of heart attack and the need for a procedure that opens blocked arteries to help blood flow to the heart in adults at risk for heart disease who aren't taking statins Nexletol (bempedoic acid
What Is NEXLETOL®? - Learn More About This Nonstatin Option How does NEXLETOL work? NEXLETOL works differently than statins NEXLETOL contains bempedoic acid, which is a nonstatin that interrupts your body’s cholesterol-making process by reducing the amount of cholesterol made by your liver