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TISCH Welcome to TISCH2 190 datasets 6,297,320 cells Tumor Immune Single-cell Hub 2 (TISCH2) is a scRNA-seq database focusing on tumor microenvironment (TME) TISCH2 provides detailed cell-type annotation at the single-cell level, enabling the exploration of TME across different cancer types
TISCH Gene Exploration Search a gene across cancer types For a single gene, TISCH2 supports exploring its expression level across different datasets or cancer types, co-expressed genes, and the clinical effect We recommend users to choose several specific cancer types rather than all cancer types for a quick response
TISCH Dataset Browser Search by the datasets For a single dataset, TISCH2 provides meta information, cell-type annotation, expression visualization, differential gene expression, GSEA results, transcription regulator analyses result, and cell-cell interaction results For multiple datasets, TISCH2 provides gene expression comparison
TISCH Tumor Immune Single-cell Hub 2 (TISCH2) is a scRNA-seq database, which aims to characterize tumor microenvironment at single-cell resolution Data collection and processing We collected tumor-related scRNA-seq studies from human and mouse Besides datasets of treatment-naive patients, those with samples treated are also included For each collected dataset, a uniform analysis pipeline
TISCH For the ICB dataset, TISCH provides ten ICB-associated signatures collected from published papers Users can select interesting signatures to explore the expression at the cell and cell type levels