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The Neuropeptide Tac2 Controls a Distributed Brain State Induced by . . . The Tac2 neuropeptide system orchestrates the complex behavioral effects of chronic social isolation stress by acting locally in multiple brain regions, suggesting the therapeutic potential of Nk3R antagonists for managing behavioral changes upon prolonged social isolation
A Second Wave for the Neurokinin Tac2 Pathway in Brain Research Tac2 pathway refers to the system formed by the NK3R, its ligand neurokinin B, and the downstream intracellular pathways Their respective gene appellations (i e , Tacr3 and Tac2) are abbreviations of the first mentions of these proteins, referred to as tachykinins
A role for Tac2, NkB, and Nk3 receptor in normal and . . . - PubMed We provide evidence that the Tac2 gene, expressed by neurons specifically within the CeM, is required for modulating fear memories Tac2 is colocalized with GAD65 and CaMKIIα but not with PKCd and Enk neurons in the CeM Moreover, the Tac2 product, NkB, and its specific receptor, Nk3R, are also involved in the consolidation of fear memories
Home | TACT2 Therapeutic Aggression Control Techniques (TACT2) is a 3-day, trauma-sensitive staff training program in behavior management, crisis de-escalation, and physical intervention Updated in May 2019 and again in May 2023, it includes extensive information on childhood trauma and adverse childhood experiences (ACEs)
Genetic marking and characterization of Tac2-expressing neurons in the . . . Behavioral analyses showed that Tac2 homozygous null mice responded normally to a series of algogenic (pain-inducing) and pruritic (itch-inducing) stimuli Tac2-Cre mice are a useful tool to mark specific subsets of neurons in the sensory ganglia, the dorsal spinal cord, and the brain
Tac2 PROVIDING TACTICAL TRAINING IN HANDGUN - SHOTGUN - RIFLE FOR CIVILIAN AND LAW ENFORCEMENT
Neuropeptidergic Control of an Internal Brain State Produced by . . . More specifically, we describe an evolutionarily conserved role for the neuropeptide tachykinin in the control of social isolation–induced aggression and review recent data that elucidate the manner by which Tac2 controls the widespread effects of social isolation on behavior in mice