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Bempedoic acid: Uses, Dosage, Side Effects, Warnings - Drugs. com Bempedoic acid (brand name Nexletol) is an oral, non-statin, LDL cholesterol-lowering treatment that may be used in adults to: lower the risk of heart attack and heart procedures (for example stent placement or bypass surgery), in those unable to take recommended statin treatment (a cholesterol-lowering medicine), or are not taking a statin, who:
Bempedoic acid (oral route) - Side effects dosage Description Bempedoic acid is used together with diet and other cholesterol-lowering medicines to reduce bad cholesterol (LDL) in patients with primary hyperlipidemia (high blood cholesterol), including heterozygous familial hypercholesterolemia (HeFH) Bempedoic acid is also used to lower the risk of heart attack and heart procedures (eg, stent placement or bypass surgery) in patients who are
Bempedoic acid: mechanism, evidence, safety, and guideline . . . Lowering low-density lipoprotein cholesterol remains foundational in reducing atherosclerotic cardiovascular disease Statins, ezetimibe, and PCSK9 inhibitors have established roles Bempedoic acid is an oral ATP‐citrate lyase (ACLY) inhibitor, relatively recently added to the lipid-lowering armamentarium In statin-intolerant or statin-suboptimal patients, plus in combination therapy, it
Bempedoic acid: A nonstatin drug for the management of . . . Bempedoic acid has been shown to provide a gradual decrease in LDL‐C when used in fusion with both statins and ezetimibe at all doses 8 Though bempedoic acid acts on the same cholesterol biosynthesis pathway as statins, the muscle‐related adverse event rate in CLEAR Serenity with bempedoic acid was not activated in skeletal muscle and did
Efficacy of Bempedoic Acid, Novel Treatment for Elevated LDL . . . By Anthony Rice Bempedoic acid is a novel non-statin drug produced by Esperion Therapeutics to treat hypercholesterolemia, elevated levels of low-density lipoprotein (LDL) cholesterol in the blood 1 In the double-blind, placebo-controlled, phase 3 2022 CLEAR Outcomes trial conducted by Esperion, bempedoic acid treatment was associated with reductions in major adverse cardiovascular events
Cleveland Clinic-Led Trial Shows That The First Drug Designed . . . Bempedoic acid is approved by the U S Food and Drug Administration as an additional treatment to help lower cholesterol in patients with certain conditions who have high cholesterol despite maximally tolerated statin therapy The trial, called CLEAR Outcomes, is the first to explore whether bempedoic acid could reduce cardiovascular outcomes
Is This New Medication Another Solution For High Cholesterol? Bempedoic acid lowered cholesterol in people who are at high risk of heart disease by 21% Last month, the Journal of the American Medical Association (JAMA) published a study that explored the use of bempedoic acid ― a fairly new medication that was approved by the FDA in 2020 ― as a cholesterol-lowering drug
Bempedoic Acid and Cardiovascular Outcomes in Statin . . . In several studies, bempedoic acid reduced the level of LDL cholesterol by 17 to 28%, a finding that, in 2020, prompted its approval by the Food and Drug Administration and the European Medicines
Bempedoic acid Patient Tips: 7 things you should know - Drugs. com Bempedoic acid is a prescription medication used along with diet and other lipid-lowering medicines in adults to help lower high cholesterol It is not a statin drug, but may be used alongside statin treatments