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Spinal muscular atrophy - Wikipedia Spinal muscular atrophy (SMA) is a rare neuromuscular disorder that results in the loss of motor neurons and progressive muscle wasting [3][4][5] It is usually diagnosed in infancy or early childhood and if left untreated it is the most common genetic cause of infant death [6]
SMA Engineering, Geomatics, Environmental Services For nearly the past decade, SMA has worked closely with several Tribal, State and Federal agencies to make this master connection plan and realignment a reality
What is Spinal Muscular Atrophy: Symptoms, Causes, and More - Cure SMA Spinal muscular atrophy (SMA) is caused by a mutation in the survival motor neuron gene 1 (SMN1) A healthy person typically has two copies of the SMN1 gene SMA occurs when both of an individual’s SMN1 copies have missing or mutated segments
Spinal Muscular Atrophy (SMA) - Childrens Hospital of Philadelphia Spinal muscular atrophy (SMA) is a genetic disease that affects the spinal cord and nerves, resulting in muscle wasting and weakness Untreated, it is a neurodegenerative, progressive disease, which can be fatal in its more severe forms What causes spinal muscular atrophy? In most cases, SMA is an autosomal recessive disease
Spinal Muscular Atrophy Update in Best Practices Spinal muscular atrophy (SMA) is an autosomal recessive progressive neurodegenerative primary motor neuron disorder caused by biallelic variants of the survival motor neuron 1 (SMN1) gene The most recent SMA best practice recommendations were published in 2018 shortly after the approval of the first SMN-enhancing treatment
Spinal muscular atrophy diagnosis and testing - SMA News Today Due to the progressive nature of spinal muscular atrophy (SMA) — a rare genetic disease — an early diagnosis is critical People with SMA who receive a timely diagnosis can start treatment immediately Most cases of SMA are caused by mutations in the SMN1 gene, leading to a deficiency of a protein called SMN or survival motor neuron protein