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Stevens Johnson syndrome toxic epidermal necrolysis: nursing management What is Stevens Johnson syndrome toxic epidermal necrolysis? Stevens Johnson syndrome toxic epidermal necrolysis (SJS TEN) is a very severe and acute skin disease, almost always caused by a drug SJS TEN is characterised by an extensive necrosis and detachment of the epidermis, which involves skin and mucosal surfaces (genitals, eyes, and mouth) The nursing care described on this page is
Severe cutaneous adverse reaction - DermNet What is a severe cutaneous adverse reaction? A severe cutaneous adverse reaction, or SCAR, refers to several distinct conditions Acute generalised exanthematous pustulosis (AGEP) Drug-induced hypersensitivity syndrome (DIHS), also known as drug reaction with eosinophilia and systemic symptoms (DRESS) Stevens–Johnson syndrome toxic epidermal necrolysis (SJS TEN) Common features can be seen
Nikolskys Sign - DermNet Using Nikolsky’s original definition strictly, his eponymous sign is the physical splitting of the epidermis creating an erosion (partial loss of the epidermis) following the application of a shearing force to the surface of the skin seen in pemphigus foliaceus However, with time the use of the sign has broadened to include other intraepidermal disorders including pemphigus vulgaris and it
Dermatological emergencies. Toxic epidermal necrolysis Created 2008 Learning objectives Recognise toxic epidermal necrolysis and its causes Clinical features Toxic epidermal necrolysis (T E N ) is characterised by fever (>38C), widespread tender erythema affecting >30% skin surface associated with mucosal involvement Erythema is followed by extensive full thickness cutaneous and mucosal necrosis and denudation within 2 or 3 days Similar
Morbilliform drug reaction (maculopapular drug eruption) - DermNet What is morbilliform drug reaction? Morbilliform drug eruption is the most common form of drug eruption Many drugs can trigger this allergic reaction, but antibiotics are the most common group The eruption may resemble exanthems caused by viral and bacterial infections A morbilliform skin rash in an adult is usually due to a drug In a child, it is more likely to be viral in origin
Cutaneous adverse reactions to antibiotics - DermNet SJS TEN Anaphylaxis Fixed drug eruption Serum sickness-like reaction Drug hypersensitivity syndrome Non-cutaneous reactions with sulfonamides include thrombocytopenia, anaemia, and electrolyte abnormalities Glycopeptides ' Red man' syndrome is a histamine -mediated reaction to the rapid infusion of vancomycin and is not an allergic reaction
Drug hypersensitivity syndrome. DRESS - DermNet Drug hypersensitivity syndrome, Drug reaction with eosinophilia and systemic symptoms, DRESS, Drug induced hypersensitivity syndrome, DIHS, DRESS syndrome Authoritative facts from DermNet New Zealand