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PSA density | Radiology Reference Article - Radiopaedia. org The PSA density (PSAD) is calculated at diagnosis of prostate cancer and is the serum prostate-specific antigen (PSA) level (ng mL) divided by the prostate gland's volume (mL), resulting in a value in the units ng mL 2 1 Prostate volume is calculated from measurements obtained using transrectal ultrasound (TRUS), MRI, or less commonly, resected pathological specimens 2-4
Prostate specific antigen | Radiology Reference Article - Radiopaedia. org Prostate specific antigen (PSA) ~30% (range 25-40%) will have a level in the normal range on re-testing, and a repeat PSA (typically a few week to months later) is recommended prior to further evaluation 8,9 PSA density PSA velocity References - - - - - -
Free total PSA ratio | Radiology Reference Article - Radiopaedia. org The free total PSA ratio (f t PSA) is the simple mathematical ratio of the free prostate specific antigen (PSA) in blood serum over the total PSA in blood serum 1,2 It is expressed as a dimensionless quantity 4 The lower the f t PSA, the higher the probability of prostate cancer 5, however, distinct cut-off values are not included in European (c 2020) 6 nor American (c 2023) guidelines 7 f
PSA velocity | Radiology Reference Article - Radiopaedia. org A PSA velocity >0 27 ng mL year may indicate the presence a clinically significant prostate cancer in patients with a negative biopsy 5 History and etymology The concept of calculating PSA kinetics was introduced in a paper by H Carter et al in 1992, although the term PSA velocity was introduced later 4
Prostate MRI (an approach) | Radiology Reference Article - Radiopaedia. org prostate specific antigen (PSA) recent level and history PSA density (can be calculated if a recent PSA level is available) PSA velocity free total PSA ratio (if PSA is between 4-10 ng mL, no use if PSA >10 ng mL ) previous systematic biopsy date and results numbers of cores location and Gleason score of positive biopsies (% core involvement)
Prostate cancer | Radiology Reference Article - Radiopaedia. org prostate-specific antigen (PSA) >10 ng mL or PSA density >0 15 ng mL tumour volume >0 5 mL (translates to a focus of ≥8 x 8 x 8 mm) extraprostatic extension (on biopsy or imaging) Gleason score >6 or ≥7 maximum number of positive biopsy samples >2 tumour volume within the biopsy sample >50% ISUP grade group 2 or 3, or higher
Benign prostate hyperplasia | Radiology Case - Radiopaedia. org In a gland of this size, the PSA density is therefore low despite the marginally raised PSA level The normal appearances of the peripheral zones are well illustrated as well as the zonal anatomy of the prostate gland 1 article features images from this case Benign prostatic hyperplasia
Prostate cancer - PI-RADS 5 | Radiology Case | Radiopaedia. org Prostate size: 42 x 40 x 40 mm (CC x AP x ML) ≈33 mL, PSA density ~0 17 ng mL 2 Hemorrhage: none Peripheral zone (PZ): bilateral linear wedge-shaped hypointensities, focal finding in the left posterior mid gland and basal zones as below: Other pelvic organs: normal Impression: A very highly suspicious lesion in the left peripheral zone
Diffuse prostate cancer - PIRADS 3 | Radiology Case - Radiopaedia. org Prostate volume 35 mL PSA density 0 12ng mL Patchy PIRADS 3 changes in both peripheral zones, right slightly more than left, most pronounced in the mid zones This is in the normal TRUS biopsy field BPH with right-sided transitional zone calcification Normal seminal vesicles No pelvic nodes No sinister bone lesion
Prostatomegaly | Radiology Reference Article - Radiopaedia. org PSA density and prostate volume calculators - Rad At Hand If any of these links are broken or for other problems and questions, please contact [email protected] References - - - Incoming Links Promoted articles (advertising) ADVERTISEMENT: Supporters see fewer no ads