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What is PIRA in Multiple Sclerosis? | National MS Society There’s an increasing amount of evidence that you may have progression independent of relapse activity, or PIRA While progression has been known for many years, this way of describing it is relatively new — and it’s creating concerns in people with MS who are hearing about it for the first time
Provisional Irish Republican Army - Wikipedia It was the most active republican paramilitary group during the Troubles It argued that the all-island Irish Republic continued to exist, and it saw itself as that state's army, the sole legitimate successor to the original IRA from the Irish War of Independence
PIRA - us. smolderingms. com Discover how addressing progression independent of relapse activity (PIRA) remains a significant unmet need in people with multiple sclerosis (MS)
Understanding PIRA and Its Clinical Significance in MS PIRA represents the gradual deterioration component that underlies progressive MS Although present from the earliest stages in virtually every patient with MS, PIRA typically manifests
Multiple Sclerosis Foundation - MS and PIRA My neurologist mentioned a new multiple sclerosis acronym to me called PIRA PIRA stands for progression independent of relapse activity PIRA was a hot topic at the European Committee for Treatment and Research in Multiple Sclerosis NeuroWebinar in May 2023
Defining progression independent of relapse activity (PIRA) in adult . . . Progression Independent of Relapse Activity (PIRA) is heterogeneously described in patients with multiple sclerosis (MS) regarding the frequency and nature of PIRA This systematic review was conducted to characterise and define the elements of PIRA
Understanding PIRA in Multiple Sclerosis - MS Views and News Detailed exploration of studies evaluating the use of highly effective treatments have unveiled the clinical concept of Progression Independent of disease activity (PIRA), or an accumulation of disability in the absence of relapse-associated worsening (RAW), in multiple sclerosis (MS)