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PFK1 Regulation: Detailed Insights for Metabolic Control Phosphofructokinase-1 (PFK1) plays a central role in glycolysis, controlling the rate of glucose breakdown and energy production Its regulation is crucial for maintaining metabolic balance, ensuring cells respond efficiently to energy demands and nutrient availability
The glycolytic enzyme phosphofructokinase-1 assembles into filaments Phosphofructokinase-1 (PFK1) is an essential glycolysis enzyme as it catalyzes the step committing glucose to breakdown Webb et al show that the liver PFK1 isoform assembles into filaments in a tetramer- and substrate-dependent manner, providing insights into the spatial organization of isoform-specific glucose metabolism in cells
Phosphofructokinase | Glycolysis, ATP, Enzymes | Britannica Phosphofructokinase, enzyme that is important in regulating the process of fermentation, by which one molecule of the simple sugar glucose is broken down to two molecules of pyruvic acid The enzyme, one of a class called transferases, catalyzes one of several specific reactions involved in this
PFKP Gene - GeneCards | PFKAP Protein | PFKAP Antibody PFKP (Phosphofructokinase, Platelet) is a Protein Coding gene Diseases associated with PFKP include Glycogen Storage Disease Vii and Intellectual Developmental Disorder, Autosomal Recessive 5 Among its related pathways are glycolysis (BioCyc) and Glycolysis (REACTOME)
CDD Conserved Protein Domain Family: PFK - National Center for . . . Phosphofructokinase, a key regulatory enzyme in glycolysis, catalyzes the phosphorylation of fructose-6-phosphate to fructose-1,6-biphosphate The members belong to PFK family that includes ATP- and pyrophosphate (PPi)- dependent phosphofructokinases
Phosphofructokinase - an overview | ScienceDirect Topics Phosphofructokinase (PFK) is a rate-controlling glycolytic enzyme Quantitative and qualitative alterations in PFK activity can significantly alter energy metabolism in cells such as erythrocytes and skeletal muscle cells that rely heavily on glucose metabolism for energy