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Primary biliary cholangitis - Symptoms and causes - Mayo Clinic Primary biliary cholangitis is an autoimmune disease in which the bile ducts are inflamed and slowly destroyed It previously was called primary biliary cirrhosis Bile is a fluid made in the liver It helps with digestion and absorbing certain vitamins It also helps the body absorb fats and get rid of cholesterol, toxins and worn-out red blood cells Ongoing inflammation in the liver can