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Estimating Creatinine Clearance in the Elderly - Medscape The MDRD and CKD-EPI equations estimate the GFR directly, whereas the Cockcroft-Gault equation estimates creatinine clearance (CrCl) While CrCl is the parameter most often used in clinical trials
Estimation of Creatinine Clearance in Morbidly Obese Patients One of the most commonly used methods for estimating GFR is through the surrogate CL cr using the Cockcroft-Gault equation [13] All Food and Drug Administration (FDA)-approved package inserts
Prescribing Metformin Using eGFR Instead of Serum Creatinine Conclusions The use of eGFR or CrCl to determine metformin eligibility instead of sCr can expand the adult population with diabetes for whom metformin is likely safe, particularly among non
Estimation of Creatinine Clearance in Morbidly Obese Patients The common use of the Cockcroft-Gault equation suggests that it will remain the method of choice for drug dosing in patients with renal impairment In contrast, the MDRD4 equation is likely to
Dapagliflozin Safe and Effective in CKD Stages 4 and 5 - Medscape In patients with CKD stage 4-5, dapagliflozin plus integrated CKD care improved total eGFR slope composite renal outcomes, composite renal and heart failure outcomes, and renal and cardiovascular