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Juvenile Arthritis Treatment Diagnosis | NIAMS Overview of Juvenile Idiopathic Arthritis (JIA) Like adults, children can develop arthritis, a condition that causes inflammation of the joints The most common type of chronic, or long-lasting, arthritis that affects children is called juvenile idiopathic arthritis (JIA) JIA is a broad term that includes several different diseases
Juvenile Idiopathic Arthritis (JIA) When present, they usually correspond to a diagnosis of rheumatoid factor-positive polyarticular JIA HLA-B27 This gene is a risk factor for enthesitis-related JIA However, some children who have enthesitis-related JIA test negative for HLA-B27, and not all those who test positive have or will ever develop the disease Other lab tests
Juvenile Idiopathic Arthritis (JIA): Research Resources To better understand the causes of JIA, researchers are studying patients with systemic JIA over time Using information gathered from periodic health evaluations and laboratory tests, the investigators expect to learn more about the genes and environmental factors involved in the disease, which may lead to new diagnostics or therapeutic
Michael J. Ombrello, M. D. | About NIAMS | NIAMS Ombrello MJ, Arthur VL, Remmers EF, Hinks A, Tachmazidou I, Grom AA, Foell D, Martini A, Gattorno M, Özen S, Prahalad S, Zeft AS, Bohnsack JF, Ilowite NT, Mellins ED, Russo R, Len C, Hilario MO, Oliveira S, Yeung RS, Rosenberg AM, Wedderburn LR, Anton J, Haas JP, Rosen-Wolff A, Minden K, Tenbrock K, Demirkaya E, Cobb J, Baskin E, Signa S, Shuldiner E, Duerr RH, Achkar JP, Kamboh MI, Kaufman
Health Lesson: Learning About Joints | NIAMS The most common type of arthritis in children is called juvenile idiopathic arthritis (JIA) There are several types of JIA, many of which are autoimmune (aa-tow-uh-MYOON) in nature In autoimmune diseases, the body mistakenly attacks its own cells and tissues Taking specific medicines and having a healthy lifestyle can help kids with JIA feel
Pediatric Translational Research Branch | NIAMS The long-term goals of the Pediatric Translational Research laboratory are to understand cellular and molecular mechanisms underlying the pathogenesis of spondyloarthritis
Translational Genetics and Genomics Section | NIAMS Ombrello MJ, Remmers EF, Tachmazidou I, Grom A, Foell D, Haas JP, Martini A, Gattorno M, Özen S, Prahalad S, Zeft AS, Bohnsack JF, Mellins ED, Ilowite NT, Russo R, Len C, Hilario MO, Oliveira S, Yeung RS, Rosenberg A, Wedderburn LR, Anton J, Schwarz T, Hinks A, Bilginer Y, Park J, Cobb J, Satorius CL, Han B, Baskin E, Signa S, Duerr RH, Achkar
All Diseases and Conditions | NIAMS NIAMS focuses on arthritis, musculoskeletal skin diseases Find causes, treatment prevention for over 50 health topics
Kan Jiang, Ph. D. | About NIAMS | NIAMS Dr Jiang received her Ph D from Aachen University in Germany and obtained her post-doctoral training at NCI and NIAMS, where she focused on the roles of transcription factors, chromatin regulators and epigenetic markers of immune cells
NIAMS IRP Presentations at the 2022 ACR Convergence Conference JIA for the Adult Rheumatology Provider: Taking Care of Children in the Biologic Age and Beyond Systemic Juvenile Arthritis: Clinical Presentation and Management Michael Ombrello, MD ( Conference Schedule )