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Charalampos Theocharopoulos - Google Scholar IA Koumprentziotis, C Theocharopoulos, D Foteinou, E Angeli, Antibody-drug conjugates for hepato-pancreato-biliary malignancies:“Magic bullets” to the rescue? C Theocharopoulos,
Beyond CTLA-4 and PD-1 Inhibition: Novel Immune Checkpoint Molecules . . . Simple Summary: Although the incorporation of immune checkpoint inhibitors (ICIs) in melanoma treatment has significantly improved prognosis for patients with advanced disease, a substantial proportion of patients have limited clinical benefit from ICIs’ administration
New Emerging Targets in Cancer Immunotherapy: The Role of B7-H3 In the review manuscript “New emerging targets in cancer immunotherapy: the role of B7-H3”, Koumprentziotis et al introduced the current insights about B7-H3 as a prognosis marker and therapeutic target
Hepatocellular carcinomas promote tumor-associated macrophage M2 . . . In the present study, 79 3% of the HCC tissue samples showed high expression of B7-H3 which was positively correlated with the number of TAMs in the evaluated cancer tissues Furthermore, high levels of TAMs or B7-H3 were associated with a shorter survival time of the HCC patients
PLA2R1 promotes DNA damage and inhibits spontaneous tumor . . . - PubMed B, C Cells were fixed in methanol and immunofluorescence staining against 53BP1 (B) and γH2AX (C) was performed with indicated antibodies Images were taken using a Nikon Fluorescence microscope and quantified with the Focinator software More than 50 nuclei were analyzed per condition