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Monacolin J Monacolin J is a polyketide that is monacolin L bearing an additional hydroxy substituent at position 8 It has a role as an antimicrobial agent, a fungal metabolite and an EC 1 1 1 34 EC 1 1 1 88 (hydroxymethylglutaryl-CoA reductase) inhibitor
Single-step production of the simvastatin precursor monacolin J by . . . Monacolin J is a key precursor for the synthesis of simvastatin (Zocor), an important drug for treating hypercholesterolemia Industrially, monacolin J is manufactured through alkaline hydrolysis of lovastatin, a fungal polyketide produced by Aspergillus terreus
Monacolin J - Wikipedia Monacolin J is a precursor to simvastatin and has potential neuroprotective activities [1][unreliable medical source?] It can be produced by total mycosynthesis
Monacolin J | C19H28O4 | CID 9905162 - PubChem Monacolin J is a polyketide that is monacolin L bearing an additional hydroxy substituent at position 8 It has a role as an antimicrobial agent, a fungal metabolite and an EC 1 1 1 34 EC 1 1 1 88 (hydroxymethylglutaryl-CoA reductase) inhibitor
Monacolin J | Lovastatin diol lactone | Cholesterol . . . Monacolin J|Lovastatin diol lactone;Antibiotic MB 530A|Autophagy|HMGCR|Monacolin J is an inhibitor of cholesterol biosynthesis, and inhibits the activity of HMG-CoA reductase
Monacolin J | CAS NO. : 79952-42-4 | GlpBio Monacolin J is an inhibitor of cholesterol biosynthesis, and inhibits the activity of HMG-CoA reductase Na salt of Monacolin J causes 50% inhibition on reductase at 1 2 μg mL [1]