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Huntingtin - Wikipedia
The Huntingtin (HTT) protein is a large, predominantly α-helical molecule composed of 3,144 amino acids and weighing approximately 348kDa in its canonical form
HTT Gene - GeneCards | HD Protein | HD Antibody
HTT (Huntingtin) is a Protein Coding gene Diseases associated with HTT include Huntington Disease and Lopes-Maciel-Rodan Syndrome Among its related pathways are Gene expression (Transcription) and Transcriptional Regulation by MECP2
Huntington Disease | Learn Science at Scitable - Nature
Today, researchers can literally "measure" the HD-associated gene, called huntingtin (HTT), by determining the number of repeats of a set of three specific bases within this gene
The Genetics of Huntingtons Disease - Perelman School of Medicine at . . .
Mutations in the HTT gene are responsible for Huntington's disease This gene codes for the huntingtin protein and within the HTT gene is a DNA sequence known as the CAG trinucleotide repeat
HTT huntingtin - NIH Genetic Testing Registry (GTR) - NCBI
Huntingtin is a disease gene linked to Huntington's disease, a neurodegenerative disorder characterized by loss of striatal neurons This is thought to be caused by an expanded, unstable trinucleotide repeat in the huntingtin gene, which translates as a polyglutamine repeat in the protein product
New Understanding of How Genetic Mutation Causes Huntington’s Disease
For 30 years, researchers have known that Huntington’s disease is caused by an inherited mutation in the Huntingtin (HTT) gene in which a three-letter DNA sequence, C-A-G, is repeated at least 40 times
Entry - *613004 - HUNTINGTIN; HTT - OMIM - (OMIM. ORG)
The HTT gene encodes huntingtin, a ubiquitously expressed nuclear protein that binds to a number of transcription factors to regulate transcription
HTT Inc - Expert Precision Metal Stamping for Wisconsin and Beyond
Since 1985, HTT has built some of the nation’s most celebrated automotive, metal stampings for gas engines, diesel engines, and appliances
Genentech: Huntingtons Disease
HD is a rare, fatal, genetic disease that causes the breakdown of nerve cells in the brain over time HD affects a person’s mental, behavioral and physical abilities, including their ability to reason, walk and speak 1 Who is affected by HD?