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Congenital Adrenal Hyperplasia (CAH) - NICHD - Eunice Kennedy Shriver . . . CAH can be categorized as classic or nonclassic types based on severity: Classic CAH is more severe than the nonclassic form It can be life threatening in newborns if it is not diagnosed Classic CAH can be caused by either 21-hydroxylase or 11-hydroxylase deficiency Nonclassic CAH is sometimes called late-onset CAH It is a milder form of
What are the symptoms of congenital adrenal hyperplasia (CAH)? Simple virilizing CAH is the moderate form of classic 21-hydroxylase deficiency This type of CAH involves less severe aldosterone deficiency Therefore, there are no severe or life-threatening sodium-deficiency symptoms in newborns Like salt-wasting CAH, simple virilizing CAH involves too little cortisol and too much androgen
About Congenital Adrenal Hyperplasia | NICHD - NICHD - Eunice Kennedy . . . CAH can be categorized as classic or nonclassic types based on severity: Classic CAH is more severe than the nonclassic form It can be life threatening in newborns if it is not diagnosed Classic CAH can be caused by either 21-hydroxylase or 11-hydroxylase deficiency Nonclassic CAH is sometimes called late-onset CAH It is a milder form of
What causes congenital adrenal hyperplasia (CAH)? CAH is caused by changes in one of several genes that lead to deficiencies in the enzymes 21-hydroxylase or11-hydroxylase The adrenal glands need these enzymes to make proper amounts of cortisol, aldosterone, androgens, and adrenaline
What are the treatments for congenital adrenal hyperplasia (CAH)? Nonclassic CAH People with nonclassic CAH may not need treatment if they do not have symptoms Individuals with symptoms are given low doses of the same cortisol replacing medication taken by people with classic CAH Symptoms of nonclassic CAH that signal that the patient may need treatment are: Early puberty; Excess body hair
NICHD Congenital Adrenal Hyperplasia Research Information In addition, CAH threatens fertility in both men and women Currently available treatments make it possible for many CAH patients to achieve health and fertility NICHD has contributed to research on treatments for CAH and continues to study ways to optimize these treatments NICHD has a long history of advances in the CAH research field
Other Congenital Adrenal Hyperplasia FAQs - NICHD Find answers to other questions about CAH, such as day care and school considerations for children with CAH and what adults with CAH need to consider about starting a family Other Congenital Adrenal Hyperplasia FAQs | NICHD - Eunice Kennedy Shriver National Institute of Child Health and Human Development
What are the symptoms of adrenal gland disorders? Symptoms of the mild form of CAH, which can be diagnosed in children or adults, may include 1: Early signs of puberty (in children) Acne; Irregular menstrual periods and possible trouble getting pregnant (in women) Excess facial hair (in women) Symptoms of the severe form of CAH, which is diagnosed in children, may include 1: Dehydration; Low
How do healthcare providers diagnose congenital adrenal hyperplasia (CAH)? Nonclassic CAH is diagnosed in childhood or adulthood, when symptoms appear To diagnose nonclassic CAH, a health care provider may: Ask whether family members have CAH Do a physical exam Take blood and urine to measure hormone levels Do a genetic test to determine if the patient has the gene change that causes CAH