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Cancer-Associated Fibroblasts in the Hypoxic Tumor Microenvironment In this article, we summarize the mechanisms underlying the hypoxic regulation of CAFs and how hypoxic CAFs affect cancer development and progression We also discuss the potential therapeutic strategies focused on targeting CAFs in the hypoxic tumor microenvironment
Cancer‑associated fibroblasts: a pivotal regulator of tumor . . . As one of the major components of the TME, Cancer‑associated fibroblasts (CAFs) are not only involved in tumorigenesis, progression, recurrence, and metastasis but also regulate the tumor-associated immune microenvironment
Cancer-Associated Fibroblasts in the Hypoxic Tumor Microenvironment - MDPI In this article, we summarize the mechanisms underlying the hypoxic regulation of CAFs and how hypoxic CAFs affect cancer development and progression We also discuss the potential therapeutic strategies focused on targeting CAFs in the hypoxic tumor microenvironment
Cancer-Associated Fibroblasts in the Hypoxic Tumor . . . In this article, we summarize the mechanisms underlying the hypoxic regulation of CAFs and how hypoxic CAFs affect cancer development and progression We also discuss the potential therapeutic strategies focused on targeting CAFs in the hypoxic tumor microenvironment
Nature Cancer | 同济大学王晨飞团队揭示泛癌中广泛存在促 . . . 2025年8月25日，同济大学生命科学与技术学院王晨飞团队在Nature Cancer上发表了文章Spatiotemporal analyses of the pan-cancer single-cell landscape reveal widespread profibrotic-associated ecotypes regulating tumor immunity。