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Bempedoic acid: Uses, Dosage, Side Effects, Warnings - Drugs. com Bempedoic acid (brand name Nexletol) is an oral, non-statin, LDL cholesterol-lowering treatment that may be used in adults to: lower the risk of heart attack and heart procedures (for example stent placement or bypass surgery), in those unable to take recommended statin treatment (a cholesterol-lowering medicine), or are not taking a statin, who:
Bempedoic acid (oral route) - Side effects dosage Description Bempedoic acid is used together with diet and other cholesterol-lowering medicines to reduce bad cholesterol (LDL) in patients with primary hyperlipidemia (high blood cholesterol), including heterozygous familial hypercholesterolemia (HeFH) Bempedoic acid is also used to lower the risk of heart attack and heart procedures (eg, stent placement or bypass surgery) in patients who are
When is Nexletol (bempedoic acid) recommended for lowering . . . The following points highlight its recommended use: Bempedoic acid is approved to reduce cardiovascular risk in statin-intolerant patients who are at high risk for, or have, cardiovascular disease 3 It is used as a monotherapy or adjunctive to other lipid-lowering therapies to achieve LDL-C targets required for cardiovascular risk reduction 3
Is This New Medication Another Solution For High Cholesterol? Bempedoic acid lowered cholesterol in people who are at high risk of heart disease by 21% Last month, the Journal of the American Medical Association (JAMA) published a study that explored the use of bempedoic acid ― a fairly new medication that was approved by the FDA in 2020 ― as a cholesterol-lowering drug
Bempedoic Acid - StatPearls - NCBI Bookshelf Bempedoic acid is a lipid-lowering agent pivotal in managing patients with elevated low-density lipoprotein cholesterol (LDL-C) levels The U S Food and Drug Administration (FDA) has sanctioned its use as an adjunct to maximally tolerated statin therapy for the reduction of LDL-C, specifically in individuals afflicted by atherosclerotic cardiovascular disease (ASCVD) and heterozygous familial
What Is NEXLETOL®? - Learn More About This Nonstatin Option How does NEXLETOL work? NEXLETOL works differently than statins NEXLETOL contains bempedoic acid, which is a nonstatin that interrupts your body’s cholesterol-making process by reducing the amount of cholesterol made by your liver
Efficacy of Bempedoic Acid, Novel Treatment for Elevated LDL . . . By Anthony Rice Bempedoic acid is a novel non-statin drug produced by Esperion Therapeutics to treat hypercholesterolemia, elevated levels of low-density lipoprotein (LDL) cholesterol in the blood 1 In the double-blind, placebo-controlled, phase 3 2022 CLEAR Outcomes trial conducted by Esperion, bempedoic acid treatment was associated with reductions in major adverse cardiovascular events
Bempedoic Acid: Uses, Dosage, Side Effects, and Interactions Learn about the indications, dosage, and potential side effects of bempedoic acid, a medication used in the treatment of hypercholesterolemia Understand its mechanism of action and important considerations for use
Bempedoic Acid Versus Statins in Primary-Prevention Patients . . . Mechanism: Bempedoic acid works by inhibiting ACL in the cholesterol-synthesis pathway; since the activating enzyme is present only in the liver (not muscle), the risk of muscle-related side-effects is diminished Frontiers Indication Use Case: Particularly useful in patients who (a) are at elevated cardiovascular risk (primary prevention or secondary), (b) cannot tolerate statins or have
Better Than Statins? The Truth About the New Cholesterol Drug Briefly: Ezetimibe reduces cholesterol absorption and interrupts enterohepatic cholesterol recirculation Bempedoic acid, a prodrug activated in the liver, lowers LDL and ApoB through hepatic-specific mechanisms Both are effective, though their LDL- and ApoB-lowering effects are smaller than those achieved with PCSK9 inhibition