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Kasabach-Merritt Syndrome - The American Journal of Medicine I read with interest the article by Albitar and Iyer 1 The Kasabach-Merritt syndrome remains an enigmatic disorder that requires an early diagnosis because of the high risk of bleeding and massive blood loss 2 There is no doubt that the mechanistic pathway of the syndrome is linked with the activation and trapping of platelets and clotting
Kasabach-Merritt Syndrome Treatment Management The Kasabach-Merritt syndrome (KMS) was first described in 1940 in a male infant with a large, rapidly enlarging discolored lesion on his thigh that was associated with consumptive
Kasabach–Merritt syndrome, not only a pediatric condition: An autopsy . . . This review highlights the clinical presentation, histopathology, management, and treatment of KMS associated with hepatic hemangiomas, Kaposiform hemangioendothelioma, and less frequently tufted angioma A clinical case is described to demonstrate the clinical presentation of a patient with KMS
Treatment of Kasabach-Merritt syndrome in infants’ maxillofacial . . . The study aims to explore the therapeutic effectiveness and side effects of local administration of urea combined with methylprednisolone for treating Kasabach-Merritt syndrome (KMS) in the maxillofacial region of infants
Rare Case of a Newborn with Kasabach-Merritt Syndrome Most patients with Kasabach-Merritt syndrome present with tufted hemangio-mas or kaposiform hemangioendotheliomas, which need to be treated because of thrombocytopenia associated with bleeding, possible disseminated intravascular coagulation (DIC), severe anemia, and eventually death
KASABACH-MERRITT SYNDROME – A COMPREHENSIVE REVIEW | INTERNATIONAL . . . Treatment aims to manage thrombocytopenia and avoid lethal outcomes According to SEOP (Spanish Society of Pediatric Oncology) guidelines for vascular tumors complicated by KMS, including vincristine, aspirin, and ticlopidine (VAT therapy)
Clinical Review: Management of Adult Kasabach-Merritt Syndrome . . . This manuscript provides a comprehensive review of KMS and discusses recent advances in the medical management of KMS We also propose a systematic therapeutic approach which would serve as a guide in the management of adult patients with KMS caused by hemangiomas