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Frontline treatment of follicular lymphoma: What will it take to change . . . Follicular lymphoma is the most common subtype of indolent lymphoma Despite multiple trials over the past decade showing improved progression-free survival with new first-line therapeutic strategies -such as anti-CD20 maintenance therapy and new glycoengineered anti-CD20 antibodies- no standardized approach has been widely adopted in routine clinical practice Several factors may explain this
Current and future therapies for follicular lymphoma Follicular lymphoma (FL) is an indolent, germinal center B cell–derived lymphoid neoplasm, for which recent advances in treatment have substantially improved patient survival However, FL remains an incurable and heterogeneous disease, with groups of patients experiencing early disease progression, histologic transformation, or a high risk of treatment-related toxicity Additionally, FL is a
Follicular Lymphoma Treatment: Whats the Latest? Follicular lymphoma is a slow-growing form of non-Hodgkin lymphoma (NHL) that arises in white blood cells called B lymphocytes It’s named for the clumps of abnormal B cells, called follicles, that develop in patients’ lymph nodes It accounts for 20-30% of all cases of NHL Although follicular lymphoma currently isn’t curable, patients can live with it for many years, making it more of
Follicular Lymphoma: A New First-Line Therapy? Diffuse large B-cell lymphoma and follicular lymphoma are two of the most common subtypes, and mantle cell lymphoma (MCL) is a particularly aggressive subtype As scientific advances in diagnosis and treatment lead to more and better treatment options, the prognosis for people with NHL continues to improve
Advances in Personalized Treatment and Prognostic Factors of Follicular . . . Follicular lymphoma is the most prevalent form of indolent B-cell lymphoma, characterized by gradual disease progression and potential survival over several decades Although the overall prognosis is typically favorable, some patients remain at risk for disease progression or transformation into a more aggressive variant Recent advancements in the treatment of relapsed or refractory
Follicular Lymphoma: Recent and Emerging Therapies, Treatment . . . Follicular lymphoma (FL) is a heterogeneous disease with varying prognosis owing to differences in clinical, laboratory, and disease parameters Although generally considered incurable, prognosis for early‐ and advanced‐stage disease has improved because of therapeutic advances, several of which have resulted from elucidation of the biologic and molecular basis of the disease The choice
The Future of Follicular Lymphoma Management . . . - ScienceDirect Progress in the therapy of follicular lymphoma (FL), the most common indolent lymphoma subtype, has been achieved in recent years with significant improvement in median overall survival Most patients diagnosed with FL will now die from other causes Multiple novel immunotherapy and other targeted therapies are now approved for relapsed and refractory disease However, early progression and
The Future of Follicular Lymphoma Management: Strategies on the Horizon Progress in the therapy of follicular lymphoma (FL), the most common indolent lymphoma subtype, has been achieved in recent years with significant improvement in median overall survival Most patients diagnosed with FL will now die from other causes