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Drug treatment for panic disorder with or without agoraphobia . . . Eligibility criteria for study selection Randomised controlled trials that included adults aged ≥18 years with a diagnosis of panic disorder, compared drugs used to treat the panic disorder, and measured the outcomes of interest, including remissions, dropouts, and adverse events
Efficacy and safety of aripiprazole or bupropion augmentation and . . . To report the first and largest systematic review and meta-analysis of randomized controlled trials (RCT) to evaluate the efficacy and safety of aripiprazole or bupropion augmentation and switching in patients with treatment-resistant depression (TRD) or major depressive dis-order(MDD)
Psychotherapies for Generalized Anxiety Disorder in Adults This systematic review and network meta-analysis of randomized clinical trials assesses the associations of various psychotherapies with short- and long-term effectiveness and acceptability for treatment of generalized anxiety disorder among adults
Bupropion—myth-busting! | CNS Spectrums | Cambridge Core Bupropion and Anxiety Bupropion is believed to exacerbate anxiety and should not be prescribed in anxious depression This is a myth Truth is that in a meta-analysis, 5 with pooled individual patient data from 10 randomized, double-blind, placebo-controlled trials, to compare the efficacy of bupropion to SSRIs in treating anxious depression
Pharmacological treatments in panic disorder in adults: a network meta . . . We only included randomised controlled trials (a type of study in which participants are assigned to a treatment group using a random method) that compared treatment with antidepressants, benzodiazepines, azapirones and placebo in adults with a diagnosis of panic disorder, with or without agoraphobia
Sertraline and Bupropion in Major Depressive Disorder - Clinical Trials . . . Specific phobia, social anxiety disorder and generalized anxiety disorders will be allowed only if judged to be currently mild and never the principal diagnosis when co-occurring with current or past MDD Panic disorder will be allowed if MDD is the principal diagnosis and panic disorder has been in remission for > 2 years
Comparative efficacy and acceptability of psychotherapies for panic . . . In recent decades, a large number of randomised controlled trials (RCTs) have been conducted to examine the effects of psychotherapies for panic disorder 4 A Cochrane systematic review and network meta-analysis (NMA) did not find high-quality unequivocal evidence to support one psychological therapy over the others for the treatment
Bupropion Sustained Release for Panic Disorder This open prospective study provides suggestive evidence that assertions in the literature that bupropion is ineffective for panic disorder may have been premature, pending randomized, placebo-controlled study
Pharmacotherapy for Anxiety Disorders - Psychiatric Clinics Anxiety disorders are the most common psychiatric illness and include disorders such as generalized anxiety disorder (GAD), panic disorder (PD), and social anxiety disorder (SAD) Psychotherapy and pharmacotherapy are both effective treatments for anxiety disorders, with efficacy between 60% and 85% Selective serotonin reuptake inhibitors and serotonin-norepinephrine reuptake inhibitors are