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Hypoparathyroidism: Symptoms Treatment - Cleveland Clinic Hypoparathyroidism is a rare but treatable condition that causes low levels of calcium in your blood Damage to your parathyroid glands during surgery and certain genetic and autoimmune diseases can cause it Treatment usually involves calcium and vitamin D supplements
Genetic disorders of parathyroid development and function Key points: Hypoparathyroidism can be an isolated endocrine disorder or part of a complex syndrome Genetic defects account for disorders of parathyroid gland formation, dysregulation of parathyroid hormone synthesis or secretion, and autoimmune destruction of the parathyroid glands
Types Causes of HypoPARAthyroidism Genetic HypoPARAthyroidism Symptoms of genetic hypoPARA present in the first few years of life, absent surgical causes There is often a family history of the condition Genetic hypoPARA may be part of a syndrome involving other organs or tissues, such as: DiGeorge Syndrome Kenny-Caffey Syndrome Autoimmune Polyglandular Syndrome (APS-1) Pearson
Hypoparathyroidism - StatPearls - NCBI Bookshelf The initial assessment of hypoparathyroidism not only includes a comprehensive history and evaluation of clinical signs and symptoms but also the identification of secondary complications that may have developed In most patients, hypoparathyroidism is clinically apparent in patients who become symptomatic immediately following neck surgery
Novel Human Genetics Evidence Confirms Estimates of Genetic . . . “ADH1 is a common genetic form of the rare endocrine disorder hypoparathyroidism ADH1 is caused by activating variants in the calcium-sensing receptor gene (CASR) and presents as hypocalcemia that can cause serious symptoms like seizures, irregular heart rhythms, muscle cramps, and breathing problems
Hypoparathyroidism: Genetics and Diagnosis - PubMed Several genetic disorders can present with hypoparathyroidism, either as an isolated disease or as part of a syndrome A positive family history and, in the case of complex diseases, characteristic comorbidities raise the clinical suspicion of a genetic disorder
Hypoparathyroidism: Genetics and Diagnosis - Oxford Academic Several genetic disorders can present with hypoparathyroidism, either as an isolated disease or as part of a syndrome A positive family history and, in the case of complex diseases, characteristic comorbidities raise the clinical suspicion of a genetic disorder