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Brain Banks - ALZFORUM This brain bank, biobank, and biospecimen bank derives its donors from the Arizona Study of Aging and Neurodegenerative Disease (AZSAND), a longitudinal clinicopathological study of elderly volunteers living in Maricopa county and metropolitan Phoenix Studies focus on Alzheimer’s and Parkinson’s, heart diseases, and cancer
Banner Sun Health Research Institute - ALZFORUM This brain bank, biobank, and biospecimen bank derives its donors from the Arizona Study of Aging and Neurodegenerative Disease (AZSAND), a longitudinal clinicopathological study of elderly volunteers living in Maricopa county and metropolitan Phoenix Studies focus on Alzheimer’s and Parkinson’s, heart diseases, and cancer
Brain Banks for Alzheimer’s, Parkinson’s Remain Underused Banner recently joined the Parkinson’s Disease Biomarkers Program, a new portal that will enable researchers to submit requests for biomarker data and associated tissue requests to the Banner brain bank, Sieber said Having brain tissue from multiple similar disorders helps researchers parse the potential contributions of unusual pathologies
Proteomics Highlight Alzheimer’s Changes in Matrisome . . . - ALZFORUM Julia TCW Boston University School of Medicine; Posted: 03 Feb 2022 Levey, Seyfried, and colleagues’ proteomic studies tell us that matrisome and cell-extracellular matrix (ECM) interaction modules are significantly upregulated in early stages of Alzheimer’s disease when amyloid and tau have accumulated, and that then post-synaptic density and protein transport modules are downregulated
Microglial Transcriptome Hints at Shortcomings of AD Model The researchers also examined microglial expression in human AD tissue They sequenced RNA from previously frozen samples of the fusiform gyrus from 33 Braak stage I-IV and 84 Braak stage III-VI cases from the Banner Research Institute tissue bank The AD samples scored about 10 percent higher for the neurodegeneration module
NB-4746 | ALZFORUM Overview Name: NB-4746 Therapy Type: Small Molecule Target Type: Other Condition(s): Amyotrophic Lateral Sclerosis U S FDA Status: Amyotrophic Lateral Sclerosis (Phase 1) Company: Nura Bio™ Inc
FDA Will Regulate Diagnostic Tests. Yes, Those for Alzheimer’s, Too. Banner Sun Health Research Institute; Posted: 10 May 2024 ; The announcement by the FDA of their Final Rule for increased oversight of laboratory developed tests (LDTs) is long overdue but very welcome Once fully implemented, this should greatly increase the scientific rigor required for certifying LDTs for clinical use
Aberrant Networks in Alzheimer’s Tied to Herpes Viruses Readhead and colleagues started with samples from the Mount Sinai Brain Bank, looking for correlations between AD and viral RNA and DNA HHV-6A and HHV-7 tended to be more abundant in the anterior prefrontal cortices (213 total samples) and superior temporal gyri (96 samples) of people with AD, likely AD, and possible AD than in controls