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Mania-related effects on structural brain changes in bipolar disorder . . . We first provide a brief overview of longitudinal case-control studies in bipolar disorder, then discuss factors that might contribute to structural brain changes, and subsequently, we provide a more detailed outline of studies reporting mania-related structural changes
What Are the Long-Term Effects of Bipolar Disorder? - WebMD Symptoms of bipolar disorder get worse when left untreated Your depression and mania episodes tend to last longer and happen more often, especially as you get older This could lead to: You
What Happens In The Manic Phase Of Bipolar Disorder? Following manic or hypomanic episodes, people with bipolar disorder often experience depressive episodes, in which a person’s mood, energy, and self-confidence are lower A depressive episode may be accompanied by changes in sleep, appetite, and interests