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MERS coronavirus EMC 2012 - Wikipedia MERS coronavirus EMC 2012 is the sixth coronavirus known to infect humans and the first human virus within betacoronavirus lineage C It is a new genotype which is related to bat coronaviruses, specifically an Egyptian tomb bat, and is not the same beta-CoV as the SARS-CoV, but is distantly related [3][6]
The Spike Protein of the Emerging Betacoronavirus EMC Uses a Novel . . . We found that the spike protein of hCoV-EMC (EMC-S) is incorporated into lentiviral particles and mediates transduction of human cell lines derived from different organs, including the lungs, kidneys, and colon, as well as primary human macrophages
HCoV-EMC - Sino Biological hCoV-EMC receptor, by which the novel coronavirus infects human, is studied Researchers engineered baby hamster kidney cells to express the human ACE2 receptor
The emerging novel Middle East respiratory syndrome coronavirus: The . . . A novel lineage C betacoronavirus, originally named human coronavirus EMC 2012 (HCoV-EMC) and recently renamed Middle East respiratory syndrome coronavirus (MERS-CoV), that is phylogenetically closely related to Tylonycteris bat coronavirus HKU4 and Pipistrellus bat coronavirus HKU5, which we discovered in 2007 from bats in Hong Kong, has
Differential Cell Line Susceptibility to the Emerging Novel Human . . . A recent cell line susceptibility study showed that HCoV-EMC can infect primate, porcine, and bat cells and therefore may jump interspecies barriers We found that HCoV-EMC can also infect civet lung fibroblast and rabbit kidney cell lines These findings have important implications for the diagnosis, pathogenesis, and transmission of HCoV-EMC
Assays for laboratory confirmation of novel human coronavirus (hCoV-EMC . . . rapid detection of hCoV-EMC by real-time reverse transcrip-tion polymerase chain reaction (RT-PCR) [2] One of these p otocols, the upE gene assay, has been used as a first-line diagnostic assay for all human cases to date More than 100 laboratori