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Emerging treatments for itch in atopic dermatitis: A review Atopic dermatitis is a chronic inflammatory skin condition with a high prevalence that is increasing The most universal symptom in patients with atopic dermatitis is pruritus; it is often the most troublesome symptom New insights on the mechanism of itch in patients with eczema have been elucidated, involving cross-talk between neural and immune systems, which have advanced our treatments
Itch in Atopic Dermatitis – What Is New? - PMC Atopic dermatitis (AD) is among the most frequent inflammatory skin diseases in humans, affecting up to 20% of children and 10% of adults in higher income countries Chronic pruritus is a disease-defining symptom of AD, representing the most
Mapping Global Research on Itch in Dermatitis A decade-long bibliometric analysis revealed rising global interest in atopic dermatitis–related itch, with an emerging focus on neural mechanisms and novel therapies
Atopic Dermatitis Itch: Scratching for an Explanation Chronic pruritus is a cardinal symptom of atopic dermatitis (AD) The mechanisms underlying atopic itch involve intricate crosstalk among skin, immune components, and neural components In this review, we explore these mechanisms, focusing on key players and interactions that induce and exacerbate itch We discuss the similarities and differences between pruritus and pain in patients with AD
Atopic Dermatitis Itch: Scratching for an Explanation INTRODUCTION Chronic itch is a defining symptom of atopic dermatitis (AD) and leads to significant morbidity The pathophysiology of pruritus in AD involves various mediators and complex neuroimmune interactions Other factors such as disruption of the skin barrier, sweat, and the skin microbiome may also exacerbate itch in these patients In this review, we aim to elucidate some of these
Effects of Dupilumab on Itch-Related Events in Atopic Dermatitis . . . Dupilumab attenuates itch and skin inflammation in patients with atopic dermatitis (AD) However, itch-related events that are improved by dupilumab remain unclear Therefore, the present study investigated changes in clinical scores, serum biomarkers, and the number of intraepidermal nerve fibers ( …
Current Clinical Options for the Management of Itch in Atopic Dermatitis Keywords: eczema, pruritus, itch, atopic dermatitis Introduction Atopic dermatitis (AD) is a common, chronic, inflammatory skin disease with an increasing prevalence in recent decades 1 The clinical features of AD include skin dryness, erythema, oozing, crusting, and lichenification, all of which can be extremely bothersome to patients
Itch in atopic dermatitis: from pathogenesis to treatment Abstract and Figures For allergists, itch is the most important symptom of atopic dermatitis (AD), and at the same time, the most difficult-to-manage complaint of atopic patient