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Prognostic risk factors for pT4 colon cancer: A retrospective cohort . . . Poor prognostic factors for pT4 colon cancer remain incompletely elucidated Understanding the oncological characteristics of pT4 colon cancer, including the tumor-specific differences between pT4a and pT4b colon cancer, can assist surgeons in providing the best possible treatment
Colorectal Cancer Stages | Rectal Cancer Staging | Colon Cancer Staging After someone is diagnosed with colorectal cancer, doctors will try to figure out if it has spread, and if so, how far This process is called staging The stage of a cancer describes how much cancer is in the body It helps determine how serious the cancer is and how best to treat it Doctors also use a cancer's stage when talking about survival statistics The earliest stage of colorectal
Prognostic Impact of pT Stage and Peritoneal Invasion in Locally . . . Background: TNM stage has been identified as an independent variable for local recurrence and survival after colon cancer resection It is still unclear whether peritoneal invasion (pT4a) is a risk factor for adverse oncologic outcome or whether these patients have better results compared with contiguous organs infiltration (pT4b), independent from nodal status (pN) Objective: The purpose of
pT4a colorectal adenocarcinoma - Humpath. com - Human pathology T4a colon adenocarcinoma; pT4a invasive colorectal adenocarcinoma Cancer involvement of the colonic serosa is designated pT4a by the American Joint Committee on Cancer Staging Manual, 7th edition The manual defines criteria for pT4a as either tumor penetration of the serosa or comingling of cancer cells and mesothelial cells in histologic
Risk of metachronous peritoneal metastases in patients with pT4a versus . . . With evolving treatment strategies aiming at prevention or early detection of metachronous peritoneal metastases (PM), identification of high-risk colon cancer patients becomes increasingly important This study aimed to evaluate differences between pT4a (peritoneal penetration) and pT4b (invasion of other organs structures) subcategories regarding risk of PM and other oncological outcomes
Minimally invasive surgery versus laparotomy of nonmetastatic pT4a . . . The aim was to compare short-term and long-term oncological outcomes between minimally invasive surgery (MIS group) and laparotomy (lap group) in nonmetastatic pT4a colorectal cancer (CRC) The study retrospectively analyzed the outcomes of 634 patients
Prognostic risk factors for pT4 colon cancer: A retrospective cohort study Patients with pT4b colon cancer and R0 resection may not have a poorer prognosis compared with those with pT4a colon cancer However, patients with pT4a colon cancer tended to have more peritoneal recurrence patterns Histology and pN status were associated with OS and RFS, and right‑sided colon cancer was also a risk factor for OS
The Staging of Colorectal Cancer: 2004 and Beyond Stage is the strongest predictor of survival for patients with colorectal cancer Accurate staging also is critical for appropriate patient management and meaningful clinical research Uniform stagin
pT4 stage II and III colon cancers carry the worst prognosis in a . . . The survival associated with pT4a versus pT4b depends on how these categories are defined with regard to Shepherd's local peritoneal involvement (LPI) In the present series, pT4 is a major indicator of poor prognosis in patients with stage II and III colon carcinoma