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Wilms Tumor Stages and Risk Groups - American Cancer Society To a large extent, your child’s treatment and prognosis (outlook) will depend on the stage, histology, and risk group of their Wilms tumor Staging is based on the results of the physical exam and imaging tests, like ultrasound and CT scans
Wilms Tumor (Nephroblastoma), Version 2. 2021, NCCN Clinical Practice . . . All patients with WT should be managed by a multidisciplinary team with experience in managing renal tumors; consulting a pediatric oncologist is strongly encouraged Treatment of WT includes surgery, neoadjuvant or adjuvant chemotherapy, and radiation therapy (RT) if needed
Surgical Considerations in the Management of Wilms Tumor Goals of Surgery for Wilms Tumor Goal is excision of the tumor in its entirety with proper staging and without spill Assessment of contralateral renal unit, collecting system, venous structures right atrium Avoid spill (and distinguish it from rupture) Proper lymph node “sampling”
Clinical presentation, diagnosis, and staging of Wilms tumor Wilms tumor is the most common kidney malignancy in children, with approximately 650 new cases diagnosed in the United States each year [1] The epidemiology, presentation, diagnosis, and staging of Wilms tumor will be reviewed here The treatment and outcome of Wilms tumor are discussed separately (See "Treatment and prognosis of Wilms tumor" )
Standard of Care in the Management of Wilms Tumors in North America In this article, the current standard of care for the management of WT will be summarized In North America, most patients are treated following Children’s Oncology Group (COG) protocols COG recommends up-front radical nephrectomy when feasible based on the criteria outlined in the Figure
Current treatment for Wilms tumor: COG and SIOP standards The diagnosis and treatment procedure of our center is to first evaluate the tumor, then conduct surgery for the patients with safe first-stage operation and develop further treatment plan according to the postoperative histology analysis and staging
Risk Stratification for Wilms Tumor: Current Approach and Future Directions Whereas the early cooperative group studies used only tumor stage for risk stratification, current Children’s Oncology Group (COG) and International Society of Pediatric Oncology (SIOP) protocols employ a multitude of prognostic factors to guide therapy
Current Therapy for Wilms’ Tumor - Oxford Academic In this section, we describe the main prognostic indicators for Wilms’ tumor These indicators will provide a backdrop for our discussion of treatment strategies Tumor Stage Staging criteria for Wilms’ tumor are based exclusively on the anatomic extent of the tumor, without consideration of genetic, biologic, or molecular markers [3]
Staging, risk groups and treatment plans for Wilms tumour Stage 2 means the tumour has spread beyond the kidney to the nearby structures There are no cancer cells in distant organs, such as the lungs The cancer is completely removed during surgery Treatment for stage 2 Wilms tumour is usually chemotherapy for 4 weeks Then surgery to remove the kidney