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Transthyretin Amyloid Cardiomyopathy (ATTR-CM) With ATTR-CM, health care professionals focus on easing the heart failure symptoms and slowing or stopping the amyloid deposits Medications are approved for hereditary transthyretin amyloidosis to treat the neuropathy that may be affecting the nerves and causing pain in hands and feet
6 Sneaky Signs You Could Have ATTR-CM - HealthCentral Transthyretin cardiac amyloidosis (or ATTR-CM for short) is a heart condition that can lead to heart failure, and it can be fatal Unfortunately, many of its symptoms are vague, which may delay
Transthyretin Amyloidosis (ATTR-CM): Types, Causes, Treatment Familial ATTR-CM symptoms most commonly occur for the first time in people over 50 However, symptoms can occur as early as your 20s or as late as your 80s Symptoms of transthyretin amyloidosis (ATTR-CM) are similar to heart failure symptoms, which include: Shortness of breath (especially when lying down or doing minimal physical activity)
Transthyretin Amyloid Cardiomyopathy (ATTR-CM) ATTR-CM typically presents with clinical signs and symptoms of progressive congestive heart failure In addition, they often have cardiac arrhythmia and conduction system disease, which may occur years before the development of heart failure
What to know about transthyretin amyloid cardiomyopathy Transthyretin amyloid cardiomyopathy (ATTR-CM) is a rare type of heart disease that can cause a thickening of the heart muscle It may lead to heart failure ATTR-CM is typically underdiagnosed
Transthyretin Amyloidosis Cardiomyopathy (ATTR-CM) A diagnosis of ATTR-CM can be confirmed with nuclear imaging, magnetic resonance imaging (MRI) or 15,16a heart biopsy It is important to confirm the type of amyloidosis, which can be done through a specialised blood test 17 ATTR-CM may be suspected when there are cardiac symptoms and or there is a family history of amyloidosis
Clinical Signs Red Flags of Transthyretin Cardiac . . . Suspect transthyretin cardiac amyloidosis* using clinical signs 1-3 *Also known as transthyretin amyloid cardiomyopathy (ATTR-CM) ATTR cardiac amyloidosis can manifest in a variety of ways due to multiorgan involvement 1-3 ATTR cardiac amyloidosis diagnosis is often delayed or missed, which is why a multidisciplinary healthcare team can help in earlier and accurate diagnosis 1-4
SIGNS AND SYMPTOMS OF ATTR-CM - Every Heart mATTRs Because of the impact of transthyretin amyloid cardiomyopathy (ATTR-CM) on the heart, the disease often presents with symptoms of heart failure such as fatigue, shortness of breath and peripheral oedema (swelling in the lower legs) Other symptoms related to the build-up of amyloid fibrils throughout the body may also occur 1,2