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- Transthyretin - Wikipedia
Transthyretin (TTR or TBPA) is a transport protein in the plasma and cerebrospinal fluid that transports the thyroid hormone thyroxine (T 4) and retinol to the liver
- Transthyretin Amyloidosis (ATTR-CM): Types, Causes, Treatment
Transthyretin amyloidosis (ATTR-CM) is a buildup of faulty proteins (fibrils) on your heart or nerves It can cause cardiomyopathy and heart failure
- Transthyretin Amyloid Cardiomyopathy (ATTR-CM) - American Heart Association
Transthyretin (trans-thy-re-tin) amyloid cardiomyopathy (ATTR-CM) is an underdiagnosed and potentially fatal disease of the heart muscle In ATTR-CM, a protein called transthyretin becomes misshapen and builds up in the heart, nerves and other organs
- A Narrative Review of the Role of Transthyretin in Health and Disease
Transthyretin (TTR) is a tetrameric transport protein highly conserved through vertebrate evolution and synthesized in the liver, choroid plexus, and retinal pigment epithelium TTR transports the thyroid hormone thyroxine and the retinol-binding protein (RBP) bound to retinol (vitamin A)
- Transthyretin amyloidosis: MedlinePlus Genetics
Transthyretin transports vitamin A (retinol) and a hormone called thyroxine throughout the body To transport retinol and thyroxine, four transthyretin proteins must attach (bind) to each other to form a four-protein unit (tetramer)
- Living with Transthyretin amyloid cardiomyopathy from a patient . . .
Background Transthyretin amyloid cardiomyopathy (ATTR-CM) is a progressive condition for which disease-modifying therapies are increasingly available However, limited research has explored the patient experience with ATTR-CM and its impact on quality of life Methods In this single-center qualitative study, we conducted semi-structured interviews with ten participants (either with ATTR-CM or
- The role of transthyretin in cell biology: impact on human . . .
Transthyretin (TTR) is an extracellular protein mainly produced in the liver and choroid plexus, with a well-stablished role in the transport of thyroxin and retinol throughout the body and brain
- Current Landscape of Therapies for Transthyretin Amyloid Cardiomyopathy
In this review, available evidence is synthesized and expert experience provided to assist clinicians in the complex navigation of treatment selection and the role of advanced therapies (heart transplantation and left ventricular assist device), as well as to identify key areas for future research
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