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- Dopamine Autoxidation Is Controlled by Acidic pH - PMC
At a pH lower than 5 6, dopamine has a half-life on a time scale of days, while at a pH of 7 4, the entirety of dopamine reserves would disappear in only a few minutes This emphasizes the role of the acidic interior of synaptic vesicles in dopamine stability and metabolism
- Effects of pH and Oxidants on the First Steps of Polydopamine . . .
Addition of Ce (IV) or Fe (III) enhances dopamine oxidation in acidic media in aerobic and anaerobic conditions by the direct oxidation of dopamine and, in the presence of oxygen, also by the autoxidation of the formed semiquinone
- Mechanistic insights into the electrochemical oxidation of . . .
From auto-oxidation experiments in presence of air oxygen in the pH range 5 8–7 0 (Fig 4) it could be shown, that formation of coloured polymeric oxidation products rapidly occurs at pH 7 0, while in solutions of lower pH dopamine oxidation is substantially lower
- Dopamine Autoxidation Is Controlled by Acidic pH - PubMed
Unlike other biogenic amines important in the central nervous system, dopamine and noradrenaline are capable of undergoing a non-enzymatic autoxidative reaction giving rise to a superoxide anion that further decomposes to reactive oxygen species
- Dopamine Autoxidation Is Controlled by Acidic pH - Frontiers
At a pH lower than 5 6, dopamine has a half-life on a time scale of days, while at a pH of 7 4, the entirety of dopamine reserves would disappear in only a few minutes This emphasizes the role of the acidic interior of synaptic vesicles in dopamine stability and metabolism
- Oxidation properties of dopamine at and near physiological . . .
At intracellular pH of the brain (pH = 7 2) dopamine (DAH) exhibits quasi-reversible oxidation to dopaminequinone (DQH) and consequent cyclization to leucoaminochrome (LAC), which further undergoes oxidation to form dopaminochrome (DC)
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