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- Reprogramming - Wikipedia
In biology, reprogramming refers to erasure and remodeling of epigenetic marks, such as DNA methylation, during mammalian development or in cell culture [1] Such control is also often associated with alternative covalent modifications of histones
- New steps forward in cell reprogramming - Harvard University
HSCI Principal Faculty member Konrad Hochedlinger, PhD, and colleagues have recently shown two ways to substantially improve the odds of successfully creating iPS cell lines: selecting immature cells rather than their more mature counterparts for reprogramming; and blocking the activity of the gene that instructs the cells to stop dividing
- Reprogramming - Latest research and news - Nature
Cell reprogramming is the process of reverting mature, specialised cells into induced pluripotent stem cells Reprogramming also refers to the erasure and re-establishment of epigenetic marks
- Direct cell reprogramming: approaches, mechanisms and progress
Direct reprogramming (also known as transdifferentiation) refers to a change in cell fate that, unlike in indirect reprogramming, does not involve a pluripotent intermediate state (usually the production of induced pluripotent stem cells)
- Cell reprogramming: methods, mechanisms and applications
Cell reprogramming represents a powerful approach to achieve the conversion cells of one type into cells of another type of interest, which has substantially changed the landscape in the field of developmental biology, regenerative medicine, disease modeling, drug discovery and cancer immunotherapy
- Chemical reprogramming for cell fate manipulation: Methods . . .
Chemical reprogramming offers an unprecedented opportunity to control somatic cell fate and generate desired cell types including pluripotent stem cells for applications in biomedicine in a precise, flexible, and controllable manner
- What is Cell Reprogramming and What Does It Mean?
Cell reprogramming is the act of reverting mature, specialised cells into induced pluripotent stem cells, also known as iPS cells This process requires a stem or progenitor cell intermediary
- Cellular reprogramming for understanding and treating human disease
Reprogramming cell fate works through the manipulation of networks governing an epigenetic state Different types of reprogramming can result in producing undifferentiated cells with varying degree of “stemness” by moving the cell back to the top of the mountain
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