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- Proteogenomics - Wikipedia
Proteogenomics is a field of biological research that utilizes a combination of proteomics, genomics, and transcriptomics to aid in the discovery and identification of peptides Proteogenomics is used to identify new peptides by comparing MS MS spectra
- Proteogenomics: concepts, applications, and computational strategies
Proteogenomics is an area of research at the interface of proteomics and genomics In this approach, customized protein sequence databases generated using genomic and transcriptomic information are used to help identify novel peptides (not present
- Intro to Proteogenomics - NCI - National Cancer Institute
Proteogenomics works to enhance our understanding of the cancer genome biology by helping prioritize genomic alterations, subtyping tumors with proteomic features, illuminating alterations to PTMs responsible for the dysregulation of cancer signaling networks, and improving the understanding of drug response and resistance to therapies
- Proteogenomics - an overview | ScienceDirect Topics
Proteogenomics is one of the most well-established areas of study of multi-omics, and the underlying technologies include next-generation sequencing (NGS) along with mass spectrometry (MS) Even though proteomics and genomes are closely related, they have remained rather isolated
- Proteogenomics: Methods and Protocols | SpringerLink
This volume presents an up-to-date overview of the current state-of-the-art protocols, and aims to put proteogenomics into a broader perspective The chapters in this book detail methods and techniques ranging from mass spectrometry to proteomics and proteogenomics and their biomedical implications and applications
- Proteogenomics - Omics tutorials
Proteogenomics is an interdisciplinary field that integrates proteomics and genomics to understand the complex relationship between an organism’s genome and its proteome The field aims to identify and characterize the entire set of proteins encoded by a genome, known as the proteome, in the context of its underlying genomic information
- Cancer proteogenomics: current impact and future prospects
In this Review we describe recent developments in proteogenomics and key findings from the proteogenomic analysis of a wide range of cancers Considerations relevant to the selection and use of
- New tool improves the detection of hidden genetic mutations
Proteogenomics combines the study of genomics and proteomics to provide a comprehensive molecular profile of diseases However, a major challenge has been the inability to accurately detect variant peptides, limiting the ability to identify genetic mutations at the protein level Existing proteomic tools often fail to capture the full diversity
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