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- ABCC8 - Wikipedia
ABCC8 ATP-binding cassette transporter sub-family C member 8 is a protein that in humans is encoded by the ABCC8 gene [5][6] ABCC8 orthologs [7] have been identified in all mammals for which complete genome data are available
- ABCC8 ATP binding cassette subfamily C member 8 [Homo sapiens (human . . .
Gene target information for ABCC8 - ATP binding cassette subfamily C member 8 (human) Find diseases associated with this biological target and compounds tested against it in bioassay experiments
- ATP-BINDING CASSETTE, SUBFAMILY C, MEMBER 8; ABCC8 - OMIM
Polymorphisms of the SUR1 (ABCC8) and Kir6 2 (KCNJ11) genes predict the conversion from impaired glucose tolerance to type 2 diabetes: the Finnish Diabetes Prevention Study
- Diabetes Mellitus Neonatal – Estudo Molecular [Gene ABCC8]
Diversas mutações no gene ABCC8 (nome oficial: “ATP-binding cassette, sub-family C (CFTR MRP), member 8”; lócus 11p15 1) estão associadas a condição conhecida como diabetes mellitus neonatal permanente Os indivíduos afetados freqüentemente apresentam baixo peso ao nascer e desenvolvem hiperglicemia no primeiro semestre de vida
- ABCC8 gene: MedlinePlus Genetics
ABCC8 gene mutations that cause permanent neonatal diabetes mellitus change single amino acids in the protein sequence These mutations result in K-ATP channels that do not close, leading to reduced insulin secretion from beta cells and impaired blood sugar control
- ABCC8 - an overview | ScienceDirect Topics
The ABCC8 gene is a high-affinity receptor for the drug sulfonylurea Sulfonylureas are a class of drugs widely used to increase insulin secretion in patients with non-insulin-dependent diabetes
- Clinical and Genetic Characteristics of ABCC8 Nonneonatal Diabetes . . .
According to the onset age, DM induced by the ABCC8 variants are classified as two major groups of disorders— ABCC8 -induced nonneonatal diabetes mellitus (ABCC8 -NNDM) and ABCC8- induced neonatal diabetes mellitus ABCC8 -NDM
- ABCC8-related Neonatal
Inheritance: ted neonatal diabetes A child of a person with ABCC8-related neonatal diabetes will have a 50% risk of inheriting the genetic change and developing diabetes during
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