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- Hepatocyte - Wikipedia
Hepatocytes display an eosinophilic cytoplasm, reflecting numerous mitochondria, and basophilic stippling due to large amounts of rough endoplasmic reticulum and free ribosomes
- The cell biology of the hepatocyte: A membrane trafficking machine
These diverse attributes are all performed by hepatocytes, the parenchymal cells of the liver As predicted, these cells possess a remarkably well-developed and complex membrane trafficking machinery that is dedicated to moving specific cargos to their correct cellular locations
- Normal Liver Histology 101 - AASLD
Hepatocyte plasma membranes are separated into sinusoidal, canalicular, and apicolateral domains The sinusoidal (basal) domain contains microvilli and faces the space of Disse, while the canalicular (apical) domain forms the bile canaliculus
- Generation of human adult hepatocyte organoids with metabolic . . . - Nature
Here we demonstrate that the combined activation of Wnt and STAT3 signalling enables long-term self-renewal of human adult hepatocyte organoids
- HepatoXcell™ Primary Human Hepatocytes - ATCC
Our dedicated technical team offers expert consultation, training videos, and on-site support to help you optimize assay development and troubleshoot challenges, ensuring you get the most out of your hepatocyte models from day one
- Hepatocytes: a key cell type for innate immunity - PMC
Hepatocytes, the major parenchymal cells in the liver, play pivotal roles in metabolism, detoxification, and protein synthesis Hepatocytes also activate innate immunity against invading microorganisms by secreting innate immunity proteins
- Proliferation tracing reveals regional hepatocyte generation in liver . . .
For organ homeostasis or regrowth after injury or disease, one or more stem cell populations is needed to rebuild lost tissue There is considerable debate about the source of new cells in the liver Two groups now identify the source of new hepatocytes (see the Perspective by Andersson)
- Heterogeneity of hepatocyte dynamics restores liver . . . - Nature
Midlobular hepatocytes are proposed to be the most plastic hepatic cell, providing a reservoir for hepatocyte proliferation during homeostasis and regeneration
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