- The technical risks of human gene editing - PMC
The application of gene editing tools in somatic stem cell therapies has raised the possibility that they could be applied in the ultimate stem cell, the one-cell embryo, allowing the genetic correction to be permanent and thus present in all cells of the resulting individual
- Gene Overexpression: Uses, Mechanisms, and Interpretation
The classical genetic approach for exploring biological pathways typically begins by identifying mutations that cause a phenotype of interest Overexpression or misexpression of a wild-type gene product, however, can also cause mutant phenotypes,
- PubMed
PubMed® comprises more than 39 million citations for biomedical literature from MEDLINE, life science journals, and online books Citations may include links to full text content from PubMed Central and publisher web sites
- Tumor Suppressor p53: Biology, Signaling Pathways, and Therapeutic . . .
TP53 is the most commonly mutated gene in human cancer with over 100,000 literature citations in PubMed This is a heavily studied pathway in cancer biology and oncology with a history that dates back to 1979 when p53 was discovered
- Gene therapy: Comprehensive overview and therapeutic applications
So far, gene therapy has been wielded in a plethora of diseases However, coherent and innocuous delivery of genes is among the major hurdles in the use of this promising therapy
- Nucleotide BLAST: Search nucleotide databases using a nucleotide query
Standard databases (nr etc ): rRNA ITS databases Genomic + transcript databases Betacoronavirus Experimental databases
- KIT KIT proto-oncogene, receptor tyrosine kinase [Homo sapiens (human . . .
Gene target information for KIT - KIT proto-oncogene, receptor tyrosine kinase (human) Find diseases associated with this biological target and compounds tested against it in bioassay experiments
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