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- Mild and ultrafast GLORI enables absolute quantification of m
This work introduces GLORI 2 0 and 3 0, enabling sensitive m6A quantification from RNA inputs as low as a few hundred cells
- GitHub - liucongcas GLORI-tools: bioinformatic pipeline for GLORI
GLORI relies on glyoxal and nitrite-mediated deamination of unmethylated adenosines while keeping m6A intact, thereby achieving specific and efficient m6A detection
- Absolute quantification of single-base m6A methylation in the . . . - PubMed
We apply GLORI to quantify the m 6 A methylomes of mouse and human cells and reveal clustered m 6 A modifications with differential distribution and stoichiometry
- GLORI-seq Services - CD Genomics
GLORI-seq's efficient workflow ensures high-quality, reproducible data, allowing you to focus on biological insights The process seamlessly combines chemical precision, sequencing, and bioinformatics for reliable m6A profiling, advancing your research in RNA regulation
- Absolute quantification of single-base m - Nature
GLORI is an unbiased, convenient method for the absolute quantification of the m6A methylome The m6A modification is mapped transcriptome-wide at single-base resolution in mammalian cells
- Absolute quantification of single-base m6A methylation in the mammalian . . .
We apply GLORI to quantify the m6A methylomes of mouse and human cells and reveal clustered m6A modifications with diferential distribution and stoichiometry
- ID 1126109 - BioProject - NCBI
We previously reported GLORI, a chemical-assisted approach firstly achieved quantitatively transcriptome-wide m6A measurement at single-base resolution Despite its advantages, GLORI suffers from lengthy reaction time and severe RNA degradation
- GLORI for absolute quantification of transcriptome-wide m
Recently, we developed GLORI, a sequencing method that enables the production of a globally absolute-quantitative m6A map at single-base resolution
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