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- Grapefruit juice dose to potantiate valium | Bluelight. org
It will make it stronger but you don't really want that You will become dependent on the GFJ to make the benzos work at all and increasing the half life is a bad thing Benzo WD is bad enough as it is, you really don't want to be dependent on something to boost it as well Your free to do as you wish of course, fair warning though
- Question About Suboxone and Grapefruit | Bluelight. org
If the elimination rate slows half-life increases By taking GFJ with bupe you are inhibiting the liver enzymes responsible for its metabolism, meaning less drug per unit time is eliminated Regarding dosing If you are on super doses of bupe, you may require more GFJ because they basically compete for the enzymes involved in their metabolism
- Opioids - Tagamet (cimetidine) as a potentiator - Bluelight. org
Yeah, I mean I know people who very elaborately and methodically dose potentiators at specific intervals, like for example, taking tagamet 1 hour before, drinking grapefruit juice 45 minutes before, taking diphenhydramine and or hydroxyzine 30 minutes before, more tagamet and more GFJ 15 minutes before, benzodiazepines, and finally, their
- Benzos - Grapefruit Juice and Xanax Question | Bluelight. org
i havent noticed any potentiation with xanax and grapefruit juice in the past, actually the only benzo i found to be potentiated by gfj in my body is valium there's studies to back this too 8 - 12 oz of 100% gfj 30-45 min before valium is supposed to add an hour or so to the tmax (time to max concentration in the blood) and be up to 3 times stronger
- Benzos - xanax potentiation | Bluelight. org
Personally when I used to try this the difference was negligible and didn't seem worth the cost of the Tagamet GFJ however is delicious and is never a waste of your hard earned dollars I've found dxm polistirex to potentiate almost everything my memory is hazy on whether it's worthwhile for benzos, but it certainly couldn't hurt
- What drugs does grapefruit juice potentiate? | Bluelight. org
For example it says that GFJ inhibits CYP3A4 and that temazepam is a substrate of CYP3A4 However from wikipedia only 10% of temazepam is processed this way and the rest is by phase II conjugation so it won't have that much of an effect
- 1st time dxm 3rd plateau questions | Bluelight. org
He weighs about 72kg He has also read about grape fruit juice and would like to potentiate the dxm He plans on getting two bottles of GFJ and drinking one glass every hour up until his initial dxm dose, one glass after the dxm dose, and one glass one hour into the trip My friend has a couple of questions Has anyone ever tried grape fruit juice?
- Tramadol potentiators | Bluelight. org
And that's exactly why GFJ IS a fairly good potentiatior: as it inhibits CYP3A4 (the unwanted one when it comes to metabolizing Codeine into Morphine) , hence, when Codeine is converted , it will undergo the hepatic metabolism by mostly CYP2D6, resulting in more moprhine, an optimized conversion and a longer half-life(as it'll take more time to
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