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- FOSB - Wikipedia
FosB and its truncated splice variants, ΔFosB and further truncated Δ2ΔFosB, are all involved in osteosclerosis, although Δ2ΔFosB lacks a known transactivation domain, in turn preventing it from affecting transcription through the AP-1 complex
- FOSB Gene - GeneCards | FOSB Protein | FOSB Antibody
FOSB (FosB Proto-Oncogene, AP-1 Transcription Factor Subunit) is a Protein Coding gene Diseases associated with FOSB include Histiocytoid Hemangioma and Pseudomyogenic Hemangioendothelioma Among its related pathways are IL-1 Family Signaling Pathways and ESR-mediated signaling
- Regulation of fosB and ΔfosB mRNA Expression: In Vivo and In Vitro . . .
The transcription factor ΔFosB, a truncated splice isoform of FosB, accumulates in brain after several types of chronic stimulation This accumulation is thought to be mediated by the unique stability of ΔFosB compared to all other Fos family proteins
- Transcription Factor FosB - an overview | ScienceDirect Topics
Transcription Factor FosB is a protein that is a member of the Fos family of transcription factors, which are regulated by neuronal activity and play a role in the transcriptional response to various stimuli in cells
- ΔFosB: A sustained molecular switch for addiction | PNAS
Increasing evidence suggests that the transcription factor ΔFosB represents one mechanism by which drugs of abuse produce relatively stable changes in the brain that contribute to the addiction phenotype
- Expression and potential role of FOSB in glioma - PMC
FOSB is reported to be an oncogene in a variety of tumors However, the expression and role of FOSB in glioma remain obscure In this study, we aimed to explore the expression of FOSB in glioma and its biological role in glioblastoma multiforme (GBM)
- FOSB - an overview | ScienceDirect Topics
FOSB is a member of the AP1 family of transcription factors that is induced in the brain, specifically in the locus coeruleus, by repeated restraint stress It plays a role in the regulation of transcription in response to chronic stress and is involved in neuroplasticity and synaptic rearrangements associated with prolonged treatments
- Expression and potential role of FOSB in glioma - Frontiers
We also reported that adjustment of FOSB expression could significantly affect the expression of cleaved caspase-3; that is to say, FOSB could regulate apoptosis
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