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- The development of skeletal muscle hypertrophy through resistance . . .
Resistance training (RT)-induced skeletal muscle hypertrophy is a highly intricate process Despite substantial advances, we are far from understanding exactly how muscle hypertrophy develops during RT The aim of the present review is to discuss new insights related to the role of skeletal muscle d …
- Mechanisms of action of methotrexate - PubMed
As one of the most utilized disease-modifying anti-rheumatic drugs, methotrexate (MTX) has revolutionized the treatment of rheumatoid arthritis as well as many other non-rheumatic chronic inflammatory diseases Far from a simple anti- proliferative agent as was once thought, our understanding of how …
- Leaky gut and autoimmune diseases - PubMed
Zonulin is the only physiologic modulator of intercellular tight junctions described so far that is involved in trafficking of macromolecules and, therefore, in tolerance immune response balance When the zonulin pathway is deregulated in genetically susceptible individuals, autoimmune disorders can occur
- Magnesium in Prevention and Therapy - PubMed
Magnesium is the fourth most abundant mineral in the body It has been recognized as a cofactor for more than 300 enzymatic reactions, where it is crucial for adenosine triphosphate (ATP) metabolism Magnesium is required for DNA and RNA synthesis, reproduction, and protein synthesis Moreover, magn …
- RNA Sequencing and Analysis - PubMed
RNA sequencing (RNA-Seq) uses the capabilities of high-throughput sequencing methods to provide insight into the transcriptome of a cell Compared to previous Sanger sequencing- and microarray-based methods, RNA-Seq provides far higher coverage and greater resolution of the dynamic nature of the tra …
- Histone acetyltransferases - PubMed
Transcriptional regulation in eukaryotes occurs within a chromatin setting and is strongly influenced by nucleosomal barriers imposed by histone proteins Among the well-known covalent modifications of histones, the reversible acetylation of internal lysine residues in histone amino-terminal domains …
- Iodine deficiency - PubMed
Iodine deficiency has multiple adverse effects in humans, termed iodine deficiency disorders, due to inadequate thyroid hormone production Globally, it is estimated that 2 billion individuals have an insufficient iodine intake, and South Asia and sub-Saharan Africa are particularly affected Howeve …
- Far infrared radiation (FIR): its biological effects and medical . . .
Far infrared (FIR) radiation (λ = 3-100 μm) is a subdivision of the electromagnetic spectrum that has been investigated for biological effects The goal of this review is to cover the use of a further sub-division (3- 12 μm) of this waveband, that has been observed in both in vitro and in vivo studies, to stimulate cells and tissue, and is
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