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- Stargardt Disease (STGD) - American Academy of Ophthalmology
Stargardt Disease (STGD) is most commonly caused by mutations in the ABCA4 gene located on chromosome 1 (OMIM 601691) and is inherited in an autosomal recessive manner
- Stargardt’s: The State of The Art in 2024
Stargardt disease was first described by German ophthalmologist Karl Stargardt in 1909 and remains the most common juvenile macular dystrophy, with an incidence of ~1 10,000 individuals worldwide
- Stargardt Disease - National Eye Institute
Vision loss usually starts in childhood — but some people with Stargardt disease don’t start to lose their vision until they’re adults There’s no treatment for Stargardt disease, but vision rehabilitation can help people make the most of their remaining vision
- Stargardt disease - Wikipedia
Other diseases may have overlapping phenotypic features with Stargardt Disease and the disease itself has multiple variants In one study, 35% of patients diagnosed with Stargardt Disease through physical ophthalmic examination were found to be misdiagnosed when subsequent genetic testing was done [15]
- Stargardt Disease Fundus Flavimaculatus - EyeWiki
Stargardt disease accounts for about 7% of all retinal degenerations, grossly affecting 1 out of every 10,000 individuals The disease usually manifests in early childhood or adolescence, but later onset has also been reported As with all autosomal conditions, males and females are equally affected No race predilection has been noted
- Stargardt Disease - Prevent Blindness
Stargardt disease afects about 1 in 10,000 people in the United States 1 This disease typically causes central vision loss in both eyes during childhood or adolescence, but sometimes it occurs later in life Central vision loss can cause dificulty recognizing faces and reading
- Stargardt’s Disease: Molecular Pathogenesis and Current . . . - MDPI
ABCA4 variants also show variable penetrance and geographical prevalence With no approved treatment, investigational therapies target different aspects of disease pathology
- Stargardt Disease - A patient’s journey across the world
Stargardt Disease (SD), caused ABCA4 gene mutations, is the most prevalent juvenile-onset inherited retinal disease As SD is rare (estimated prevalence 1 10,000) with no approved treatment, we sought to better understand the SD patient journey from disease onset to clinical diagnosis and management across the world
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