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- Cycloastragenol - Wikipedia
Cycloastragenol is a triterpenoid isolated from various legume species in the genus Astragalus that is purported to have telomerase activation activity A preliminary in vitro study on human CD4 and CD8 T cells found that cycloastragenol may moderately increase telomerase activity and inhibit the onset of cellular senescence
- A comprehensive review of cycloastragenol: Biological activity . . .
Cycloastragenol (CAG) is a sapogenin of Astragaloside IV (AG-IV), isolated from the dried roots of legumes Astragalus mongolica or Astragalus membranaceus Cycloastragenol has a steroidal skeleton of tetracyclic triterpene and possess diverse pharmacological activities such as anti-aging, anti-inflammatory, anti-fibrosis, pro-wound healing
- Cycloastragenol: An exciting novel candidate for age-associated . . .
Cycloastragenol (CAG) is a triterpenoid saponin compound and a hydrolysis product of the main active ingredient in Astragalus membranaceus (Fisch ) Bunge An increasing body of evidence has indicated that CAG has a wide spectrum of pharmacological
- Cycloastragenol is a potent telomerase activator in neuronal cells . . .
Cycloastragenol (CAG) is an aglycone of astragaloside IV It was first identified when screening Astragalus membranaceus extracts for active ingredients with antiaging properties The present study demonstrates that CAG stimulates telomerase activity and cell proliferation in human neonatal keratino …
- Cycloastragenol: A Novel Senolytic Agent That Induces Senescent Cell . . .
In the present study, we identified that cycloastragenol (CAG), a secondary metabolite isolated from Astragalus membrananceus, delays age-related symptoms in mice through its senolytic activity against SCs
- Cycloastragenol: pharmacokinetics, activities and side effects
Cycloastragenol is a compound that exhibits diverse pharmacological activities It activates telomerase, which leads to the lengthening of telomeres and a decrease in DNA damage
- Cycloastragenol upregulates SIRT1 expression, attenuates apoptosis and . . .
Cycloastragenol (CAG) is the active form of astragaloside IV isolated from Astragalus Radix, which displays multiple pharmacological effects Silent information regulator 1 (SIRT1), a class III
- Cycloastragenol | C30H50O5 | CID 13943286 - PubChem
Cycloastragenol is a sapogenin that is the aglycone derivative of astragaloside IV, a major saponin extracted from the root of Astragalus membranaceus It has a role as a metabolite
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