Chemoenzymatic synthesis - Nature This Collection aims to present the latest progress in the chemoenzymatic syntheses of high-value-added organic compounds We welcome both experimental and theoretical studies
Recent Advances in the Chemoenzymatic Synthesis of Bioactive Natural . . . In light of the unparalleled regio- and stereoselectivity of enzymatic transformations and the reaction diversity of contemporary organic chemistry, chemoenzymatic strategies hold enormous potential for streamlining access to important bioactive molecules
Chemoenzymatic Synthesis of Glycans and Glycoconjugates This chapter summarizes recent developments in the use of (mutant) glycosidases and glycosyltransferases for the synthesis of tailored glycans, including combinations of both enzyme classes and in conjunction with chemically synthesized intermediates are presented
Guiding chemoenzymatic synthesis - Nature Chemical Biology Chemoenzymatic methods combine chemical synthesis with enzymatic reactions that work under milder reaction conditions and can offer advantages in stereospecificity and regioselectivity
Chemoenzymatic Synthesis: Combining Chemistry and Biology for Drug . . . Chemoenzymatic synthesis is an innovative approach that combines the precision of chemical synthesis with the efficiency and selectivity of biocatalysis to create complex bioactive molecules, offering a powerful strategy for drug discovery
Chemoenzymatic Synthesis Planning Guided by Reaction Type Score Herein, we report a reaction type score (RTscore)-guided chemoenzymatic synthesis planning (RTS-CESP) strategy Briefly, the RTscore is trained using a text-based convolutional neural network (TextCNN) to distinguish synthesis reactions from decomposition reactions and evaluate synthesis efficiency