- Cell: Cell Press
Cell publishes findings of unusual significance in any area of experimental biology, including but not limited to cell biology, molecular biology, neuroscience, immunology, virology and microbiology, cancer, human genetics, systems biology, signaling, and disease mechanisms and therapeutics
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Publisher of over 50 scientific journals across the life, physical, earth, and health sciences, both independently and in partnership with scientific societies including Cell, Neuron, Immunity, Current Biology, AJHG, and the Trends Journals
- Issue: Cell
Despite initial forays into clinical settings, single-cell technologies do not yet routinely inform medical decision-making Here, we identify and categorize barriers hindering the clinical deployment of single-cell omics
- The structure of human sweetness: Cell
Over 20 years ago, the mammalian sweet taste receptor was identified using a combination of genetics, cell-based assays, and mouse knockout studies 1,2,3 Notably, a single sweet receptor recognizes the diverse universe of sweet-tasting compounds, including natural sugars, artificial sweeteners, D-amino acids, and a class of intensely sweet
- CD36-mediated endocytosis of proteolysis-targeting chimeras: Cell
In our studies, pull-down of potential interacting proteins from cell membrane lysates with biotinylated probes and sequential mass spectrometry analyses identified key clathrin endocytic cascade-associated proteins, including clathrin heavy-chain-1, clathrin adaptor protein 2 complex (AP-2), and Rab5 20 Rab-5 KD decreased protein degradation
- Long-term imaging of individual ribosomes reveals ribosome . . . - Cell Press
To quantify the contribution of cell-to-cell heterogeneity to single ribosome elongation rate heterogeneity, we randomly selected two ribosomes translating two different socRNAs within the same cell (Figure S2 F) and employed an approach used for the noise decomposition into intrinsic and extrinsic components, which have orthogonal contribution
- A host organelle integrates stolen chloroplasts for animal . . .
These slugs feed on marine algae by piercing cell walls with their radula, sucking out the cell contents, 1 and ingesting and sequestering stolen, photosynthetically active chloroplasts into the cells lining their intestinal diverticula 2,3,4,5,6 (Figure 1 A)
- Meningeal lymphatics-microglia axis regulates synaptic physiology: Cell
Gene Ontology (GO) analysis of significantly upregulated genes in microglia (adj p value < 0 05, log 2 FC > 0 2; Figure S3 D) revealed GO terms for “antigen processing and presentation of exogenous peptide,” “response to type II interferon,” and “positive regulation of leukocyte cell-cell interaction ”
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