- Urolithin A improves muscle strength, exercise performance, and . . .
We present results from a randomized, placebo-controlled trial in middle-aged adults where we administer a postbiotic compound Urolithin A (Mitopure), a known mitophagy activator, at two doses for 4 months (NCT03464500)
- Urolithin A improves muscle strength, exercise performance, and . . .
We present results from a randomized, placebo-controlled trial in middle-aged adults where we administer a postbiotic compound Urolithin A (Mitopure), a known mitophagy activator, at two doses for 4 months (NCT03464500)
- The mitophagy activator urolithin A is safe and induces a molecular . . .
Here, we report the results of a first-in-human clinical trial in which we administered UA, either as a single dose or as multiple doses over a 4-week period, to healthy, sedentary elderly individuals We show that UA has a favourable safety profile (primary outcome)
- The mitophagy activator urolithin A is safe and induces a molecular . . .
In this report, we detail the outcome of a first-in-human, randomized, double-blind, placebo-controlled clinical study with UA in healthy, sedentary elderly individuals, and describe its safety,
- Bioengineering the metabolic network of CAR T cells with . . . - Cell Press
By screening a small library of molecules involved in these processes and mitochondrial metabolism, we identified GLP-1RA semaglutide (SG) and Urolithin A (UrA) as promising candidates for enhancing CAR T cell persistence and anti-tumor activity
- Mitophagy Activation by Urolithin A to Target Muscle Aging
In this review, we explore the biology of Urolithin A and the clinical evidence of its impact on promoting healthy skeletal muscles during age-associated muscle decline Skeletal muscle aging is associated with progressive muscle mass and strength decline
- Urolithin A attenuates auditory cell senescence by activating mitophagy
Urolithin A (UA) induces mitophagy in various mammalian cells This study was aimed at investigating the effect of the mitophagy activator, UA, on premature senescent auditory cells
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