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- Trigeminovascular system - Wikipedia
The trigeminovascular system (TVS) refers to neurons and their axonal projections within the trigeminal nerve that project to the cranial meninges and meningeal blood vessels [1][2] residing on the brain's surface [3]
- Pathophysiology of Migraine | Science of Migraine
The trigeminovascular system, which relays head pain signals to the brain, plays a key role in migraine pathophysiology and has components in the periphery (ie, outside the blood-brain barrier) as well as in the central nervous system (CNS) (ie, inside the blood-brain barrier) 3,48-50
- What Happens to the Body During a Migraine Attack?
In people who have migraine, this system releases brain chemicals that cause inflammation in the brain, vasodilation, and leaks of plasma protein The trigeminovascular system is thought to play a role in how long and how intense a migraine is
- Trigeminal Nerve and Migraines: What’s the Connection?
According to a review published in Lancet Neurology, this system is thought to be ground zero for migraine activity in the brain Once the nerve is triggered in some way it releases chemicals
- The Trigeminovascular System and Migraine - Neurotorium
The trigeminovascular system is recognized as the anatomical and physiological substrate of migraine Within this system, migraine-inducing and vasodilatory substances are thought to initially cause the activation of pain-sensitive first-order neurons that innervate meningeal blood vessels
- The Trigeminovascular System: Key To Understanding Migraine
The trigeminovascular system plays a crucial role in the pathophysiology of migraine, a complex neurological disorder affecting millions worldwide This intricate network of nerves and blood vessels forms the cornerstone of our understanding of migraine mechanisms
- The fifth cranial nerve in headaches - The Journal of Headache and Pain
The trigeminovascular system has long been a focus of elucidating primary headache pathophysiology [14] It consists of the trigeminal neurons innervating the cerebral arteries, the pial and dural blood vessels, and sinuses [15]
- Rare trigeminovascular signs during migraine attack
Trigeminovascular system activation is proposed as a final common pathway in the pathogenesis of migraine attacks 1 Upon activation of the trigeminal afferents surrounding pial and dural vessels, signals pass through the trigeminal ganglion to the trigeminal nucleus caudalis
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